@inproceedings{748af8e9e63041a8aa4a034bf582e8d1,
title = "Protein profile study of Pap smear and tissue of cervix by high performance liquid chromatography- laser induced fluorescence",
abstract = "HPLC combined with laser induced fluorescence provides a very sensitive method for the separation and identification of the many proteins present in clinical samples. Protein profiles of clinical samples like Pap smear and tissue samples, from subjects with cervical cancer and normal volunteers, were recorded using HPLC-LIF. The protein profiles were analyzed by Principal Component Analysis (PCA). The profiles were characterized by parameters like scores of the factors, sum of squared residuals, and Mahalanobis Distance, derived from PCA. Parameters of each sample were compared with those of a standard set and Match/ No Match results were generated. Good discrimination between normal and malignant samples was achieved with high sensitivity and specificity.",
author = "Sujatha and Lavanya Rai and Pratap Kumar and Krishnanand, {B. R.} and Mahato, {K. K.} and George, {Sajan D.} and Kartha, {V. B.} and C. Santhosh",
year = "2007",
doi = "10.1117/12.699711",
language = "English",
isbn = "0819465542",
volume = "6441",
series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",
booktitle = "Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues V",
note = "Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues V ; Conference date: 22-01-2007 Through 24-01-2007",
}
