TY - GEN
T1 - Protein structure prediction on 2D square HP lattice with revised fitness function
AU - Dubey, Sandhya Parasnath
AU - Gopalakrishna Kini, N.
AU - Balaji, S.
AU - Sathish Kumar, M.
N1 - Publisher Copyright:
© 2017 IEEE.
PY - 2017/11/30
Y1 - 2017/11/30
N2 - In order to understand the structure and folding of proteins, Hydrophobic-Polar (HP) model on 2D square lattice is one of the most explored models but parity problem of square lattice make it inefficient for biological applications. This work is dedicated to solve parity issues in 2D square lattice model. This work proposes a revised energy function and presents a case study for protein structure prediction (PSP). A novel approach to evaluate the structure modeling and protein folding problem over HP model is presented in this paper. This evaluation approach may enhance the quality and effectiveness of the computational approaches developed to address the PSP at coarse level.
AB - In order to understand the structure and folding of proteins, Hydrophobic-Polar (HP) model on 2D square lattice is one of the most explored models but parity problem of square lattice make it inefficient for biological applications. This work is dedicated to solve parity issues in 2D square lattice model. This work proposes a revised energy function and presents a case study for protein structure prediction (PSP). A novel approach to evaluate the structure modeling and protein folding problem over HP model is presented in this paper. This evaluation approach may enhance the quality and effectiveness of the computational approaches developed to address the PSP at coarse level.
UR - https://www.scopus.com/pages/publications/85042640814
UR - https://www.scopus.com/inward/citedby.url?scp=85042640814&partnerID=8YFLogxK
U2 - 10.1109/ICACCI.2017.8126094
DO - 10.1109/ICACCI.2017.8126094
M3 - Conference contribution
AN - SCOPUS:85042640814
VL - 2017-January
T3 - 2017 International Conference on Advances in Computing, Communications and Informatics, ICACCI 2017
SP - 1732
EP - 1736
BT - 2017 International Conference on Advances in Computing, Communications and Informatics, ICACCI 2017
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 2017 International Conference on Advances in Computing, Communications and Informatics, ICACCI 2017
Y2 - 13 September 2017 through 16 September 2017
ER -