TY - JOUR
T1 - Pure erythroleukemia
T2 - A case report and literature review
AU - Khanna, Ruchee
AU - Nayak, Deepak
AU - Manohar, Chethan
AU - Seshadri, Shubha
AU - Belurkar, Sushama V.
PY - 2011/8/18
Y1 - 2011/8/18
N2 - Pure erythroleukemia is a rare hematopoietic neoplasm, seldom reported in literature. Varied reports suggest a prevalence of 3-5% of all AML. We report one such case, presenting with non classical symptoms in a 65 year old lady. Peripheral smear examination and complete hemogram revealed a pancytopenic profile with circulating basophilic erythroblasts. Bone marrow study yielded erythroid hyperplasia with abundance of PAS positive proerythroblasts and dyspoiesis in other lineages. Pure erythroleukemias are known to carry a poor response to standard chemotherapy. The present case is a testament not only to the rarity of the disease but also for a reminder that such an aggressive neoplasm can indeed present in the most inconspicuous manner.
AB - Pure erythroleukemia is a rare hematopoietic neoplasm, seldom reported in literature. Varied reports suggest a prevalence of 3-5% of all AML. We report one such case, presenting with non classical symptoms in a 65 year old lady. Peripheral smear examination and complete hemogram revealed a pancytopenic profile with circulating basophilic erythroblasts. Bone marrow study yielded erythroid hyperplasia with abundance of PAS positive proerythroblasts and dyspoiesis in other lineages. Pure erythroleukemias are known to carry a poor response to standard chemotherapy. The present case is a testament not only to the rarity of the disease but also for a reminder that such an aggressive neoplasm can indeed present in the most inconspicuous manner.
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M3 - Article
AN - SCOPUS:80051634239
SN - 1540-2649
VL - 7
JO - Internet Journal of Hematology
JF - Internet Journal of Hematology
IS - 2
ER -