Abstract
Non immediate allergic reactions (NIRs) to drugs, due to specific immunologic mechanisms, can be induced by many commercially available drugs Maculopapular exanthema (MPE) is the one among the commonest manifestation following NIRs. Cytokines are known to play a dominant role in causing MPE. T helper 1 (Th1) cytokines and CD4 (+) T cells play a very pivotal role in the pathogenesis of this condition. As a part of pharmaovigilance program we hereby report a case of Maculopapular rash induced by pyrazinamide in a patient treated for pulmonary tuberculosis. The causality, severity, and preventability assessment of the adverse drug reaction was done to establish a causal relationship.
| Original language | English |
|---|---|
| Pages (from-to) | 2601-2604 |
| Number of pages | 4 |
| Journal | Research Journal of Pharmaceutical, Biological and Chemical Sciences |
| Volume | 7 |
| Issue number | 4 |
| Publication status | Published - 01-07-2016 |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
All Science Journal Classification (ASJC) codes
- General Biochemistry,Genetics and Molecular Biology
- Pharmacology, Toxicology and Pharmaceutics(all)
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