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Pyrazinoic acid hydrazide derivatives : Synthesis and antimycobacterial activities

  • P.B. Miniyar
  • , A.R. Bhat

Research output: Contribution to journalArticlepeer-review

Abstract

A series of substituted pyrazinoic acid hydrazides has been prepared and examined for their in-vitro activity against Mycobacterium tuberculosis. The representative compounds of each series screened for antitubercular studies were active against the test organism Mycobacterium tuberculosis H37Rv strain. Pyrazinamide was hydrolyzed and esterified to get ethyl pyrazinoate. Ethyl pyrazinoate was reacted with substituted aromatic acid hydrazides and phenoxy acetic acid hydrazides to yield respective hydrazide derivatives.
Original languageEnglish
Pages (from-to)155-156
Number of pages2
JournalIndian Journal of Heterocyclic Chemistry
Volume9
Issue number2
Publication statusPublished - 1999

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

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