Abstract
Micronuclei (MN) induction in the mouse bone marrow polychromatic erythrocytes (PCE) and normochromatic erythrocytes (NCE) was studied 24 h after whole body exposure to 4 Gy of gamma radiation with or without a single intraperitoneal injection of 25 mg/kg to 150 mg/kg of 50% methanolic extract of Phyllanthus niruri (whole aerial part). The extract significantly reduced the radiation-induced MN induction in both PCE and NCE and increased the ratio of PCE to NCE. The effect increased linearly with extract dose from 25 to 125 mg/kg.
| Original language | English |
|---|---|
| Pages (from-to) | 1245-1247 |
| Number of pages | 3 |
| Journal | Current Science |
| Volume | 78 |
| Issue number | 10 |
| Publication status | Published - 25-05-2000 |
All Science Journal Classification (ASJC) codes
- General