TY - JOUR
T1 - Recombinant activated factor VII in the management of acute fatty liver of pregnancy
T2 - A case report
AU - Supriya, K.
AU - Thunga, Suchitra
AU - Narayanan, Athira
AU - Singh, Prakhar
N1 - Publisher Copyright:
© 2015 The Authors. Journal of Obstetrics and Gynaecology Research © 2015 Japan Society of Obstetrics and Gynecology
PY - 2015/1/1
Y1 - 2015/1/1
N2 - A 20-year-old woman, primigravida at 36+4 weeks' gestation presented with malaise, vomiting for 1 week, yellowish discoloration of the eyes for 3 days and loss of fetal movements. A clinical diagnosis of acute fatty liver with intrauterine fetal demise was made. Labor was induced with prostaglandin E2 gel and delivered vaginally. The post-partum period was complicated by atonic post-partum hemorrhage, an episode of seizure, recurrent hypoglycemic attack, hypokalemia and continuing coagulopathy. Supportive management in the intensive care unit using blood and blood products and injection recombinant activated factor VIIa to arrest the bleeding resulted in a successful outcome.
AB - A 20-year-old woman, primigravida at 36+4 weeks' gestation presented with malaise, vomiting for 1 week, yellowish discoloration of the eyes for 3 days and loss of fetal movements. A clinical diagnosis of acute fatty liver with intrauterine fetal demise was made. Labor was induced with prostaglandin E2 gel and delivered vaginally. The post-partum period was complicated by atonic post-partum hemorrhage, an episode of seizure, recurrent hypoglycemic attack, hypokalemia and continuing coagulopathy. Supportive management in the intensive care unit using blood and blood products and injection recombinant activated factor VIIa to arrest the bleeding resulted in a successful outcome.
UR - https://www.scopus.com/pages/publications/84984650169
UR - https://www.scopus.com/pages/publications/84984650169#tab=citedBy
U2 - 10.1111/jog.12684
DO - 10.1111/jog.12684
M3 - Article
C2 - 25809227
AN - SCOPUS:84984650169
SN - 1341-8076
SP - 1122
EP - 1125
JO - Journal of Obstetrics and Gynaecology Research
JF - Journal of Obstetrics and Gynaecology Research
ER -