Recurrent metastatic mixed germ cell tumor of central nervous system with additional seminomatous component

Shrijeet Chakraborti; Hema Kini; Santosh Rai; Ashvini Kumar

doi:10.4103/0975-2870.150498

Recurrent metastatic mixed germ cell tumor of central nervous system with additional seminomatous component

Shrijeet Chakraborti, Hema Kini, Santosh Rai, Ashvini Kumar

Research output: Contribution to journal › Article › peer-review

Abstract

Mixed germ cell tumors (GCTs) are aggressive tumors owing to poor response to therapy, frequent recurrence and metastasis. We present here a case of 29-year-old male with recurrent metastatic mixed GCT in the left parietal lobe, with right testicular primary. Interestingly, the recurrent tumor exhibited a seminomatous component, in addition to yolk sac tumor and embryonal carcinoma. The patient was treated with surgery, cranial radiotherapy and cisplatin-based chemotherapy. The metastatic intracranial tumor recurred twice and the patient died 18 months after the first appearance of central nervous system metastasis.

Original language	English
Pages (from-to)	407-410
Number of pages	4
Journal	Medical Journal of Dr. D.Y. Patil University
Volume	8
Issue number	3
DOIs	https://doi.org/10.4103/0975-2870.150498
Publication status	Published - 01-05-2015

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Medicine(all)

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title = "Recurrent metastatic mixed germ cell tumor of central nervous system with additional seminomatous component",

abstract = "Mixed germ cell tumors (GCTs) are aggressive tumors owing to poor response to therapy, frequent recurrence and metastasis. We present here a case of 29-year-old male with recurrent metastatic mixed GCT in the left parietal lobe, with right testicular primary. Interestingly, the recurrent tumor exhibited a seminomatous component, in addition to yolk sac tumor and embryonal carcinoma. The patient was treated with surgery, cranial radiotherapy and cisplatin-based chemotherapy. The metastatic intracranial tumor recurred twice and the patient died 18 months after the first appearance of central nervous system metastasis.",

author = "Shrijeet Chakraborti and Hema Kini and Santosh Rai and Ashvini Kumar",

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AU - Chakraborti, Shrijeet

AU - Kini, Hema

AU - Rai, Santosh

AU - Kumar, Ashvini

PY - 2015/5/1

Y1 - 2015/5/1

N2 - Mixed germ cell tumors (GCTs) are aggressive tumors owing to poor response to therapy, frequent recurrence and metastasis. We present here a case of 29-year-old male with recurrent metastatic mixed GCT in the left parietal lobe, with right testicular primary. Interestingly, the recurrent tumor exhibited a seminomatous component, in addition to yolk sac tumor and embryonal carcinoma. The patient was treated with surgery, cranial radiotherapy and cisplatin-based chemotherapy. The metastatic intracranial tumor recurred twice and the patient died 18 months after the first appearance of central nervous system metastasis.

AB - Mixed germ cell tumors (GCTs) are aggressive tumors owing to poor response to therapy, frequent recurrence and metastasis. We present here a case of 29-year-old male with recurrent metastatic mixed GCT in the left parietal lobe, with right testicular primary. Interestingly, the recurrent tumor exhibited a seminomatous component, in addition to yolk sac tumor and embryonal carcinoma. The patient was treated with surgery, cranial radiotherapy and cisplatin-based chemotherapy. The metastatic intracranial tumor recurred twice and the patient died 18 months after the first appearance of central nervous system metastasis.

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Recurrent metastatic mixed germ cell tumor of central nervous system with additional seminomatous component

Abstract

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