Reduced toxicity and enhanced antitumor efficacy of betacyclodextrin plumbagin inclusion complex in mice bearing Ehrlich ascites carcinoma

U. V. Singh; N. Udupa

Reduced toxicity and enhanced antitumor efficacy of betacyclodextrin plumbagin inclusion complex in mice bearing Ehrlich ascites carcinoma

U. V. Singh
, N. Udupa^*

^*Corresponding author for this work

Department of Pharmaceutics, Manipal College of Pharmaceutical Sciences, Manipal

Research output: Contribution to journal › Article › peer-review

58 Citations (Scopus)

Abstract

Inclusion complex of plumbagin was prepared with betacyclodextrin employing neutralization method. The toxicity of the drug was reduced and the antitumor efficacy was enhanced on complexation with betacyclodextrin.

Original language	English
Pages (from-to)	171-175
Number of pages	5
Journal	Indian Journal of Physiology and Pharmacology
Volume	41
Issue number	2
Publication status	Published - 04-1997

All Science Journal Classification (ASJC) codes

Physiology
Pharmacology
Physiology (medical)

Cite this

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title = "Reduced toxicity and enhanced antitumor efficacy of betacyclodextrin plumbagin inclusion complex in mice bearing Ehrlich ascites carcinoma",

abstract = "Inclusion complex of plumbagin was prepared with betacyclodextrin employing neutralization method. The toxicity of the drug was reduced and the antitumor efficacy was enhanced on complexation with betacyclodextrin.",

author = "Singh, \{U. V.\} and N. Udupa",

year = "1997",

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language = "English",

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journal = "Indian Journal of Physiology and Pharmacology",

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AU - Singh, U. V.

AU - Udupa, N.

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N2 - Inclusion complex of plumbagin was prepared with betacyclodextrin employing neutralization method. The toxicity of the drug was reduced and the antitumor efficacy was enhanced on complexation with betacyclodextrin.

AB - Inclusion complex of plumbagin was prepared with betacyclodextrin employing neutralization method. The toxicity of the drug was reduced and the antitumor efficacy was enhanced on complexation with betacyclodextrin.

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M3 - Article

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AN - SCOPUS:0030983424

SN - 0019-5499

VL - 41

SP - 171

EP - 175

JO - Indian Journal of Physiology and Pharmacology

JF - Indian Journal of Physiology and Pharmacology

IS - 2

ER -

Reduced toxicity and enhanced antitumor efficacy of betacyclodextrin plumbagin inclusion complex in mice bearing Ehrlich ascites carcinoma

Abstract

All Science Journal Classification (ASJC) codes

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