Regiospecific reaction: Synthesis and biological assay of some sydnone and triazole-containing Mannich derivatives

Balakrishna Kalluraya; Ganesha Rai; Satheesha Rai; Shalini Shenoy

Regiospecific reaction: Synthesis and biological assay of some sydnone and triazole-containing Mannich derivatives

Balakrishna Kalluraya^*
, Ganesha Rai
, Satheesha Rai
, Shalini Shenoy

^*Corresponding author for this work

Department of Microbiology, Kasturba Medical College, Mangalore

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

Condensation of 3-substituted-4-amino-1,2,4-triazole-5-thiones 3 with 3-aryl-sydnone-4-carboxaldehyde 5 afforded a series of Schiff's bases 6. These Schiff's bases underwent Mannich reaction regiospecifically with morpholine and formaldehyde to give Mannich bases 7. The new compounds were characterized by spectral and analytical data. Biological screening results showed promising antibacterial and antifungal activities for these compounds.

Original language	English
Pages (from-to)	127-130
Number of pages	4
Journal	Indian Journal of Heterocyclic Chemistry
Volume	14
Issue number	2
Publication status	Published - 01-10-2004

All Science Journal Classification (ASJC) codes

Organic Chemistry

Cite this

@article{23e573604101405ba921caa577592dd2,

title = "Regiospecific reaction: Synthesis and biological assay of some sydnone and triazole-containing Mannich derivatives",

abstract = "Condensation of 3-substituted-4-amino-1,2,4-triazole-5-thiones 3 with 3-aryl-sydnone-4-carboxaldehyde 5 afforded a series of Schiff's bases 6. These Schiff's bases underwent Mannich reaction regiospecifically with morpholine and formaldehyde to give Mannich bases 7. The new compounds were characterized by spectral and analytical data. Biological screening results showed promising antibacterial and antifungal activities for these compounds.",

author = "Balakrishna Kalluraya and Ganesha Rai and Satheesha Rai and Shalini Shenoy",

year = "2004",

month = oct,

day = "1",

language = "English",

volume = "14",

pages = "127--130",

journal = "Indian Journal of Heterocyclic Chemistry",

issn = "0971-1627",

publisher = "Connect Journals",

number = "2",

}

TY - JOUR

T1 - Regiospecific reaction

T2 - Synthesis and biological assay of some sydnone and triazole-containing Mannich derivatives

AU - Kalluraya, Balakrishna

AU - Rai, Ganesha

AU - Rai, Satheesha

AU - Shenoy, Shalini

PY - 2004/10/1

Y1 - 2004/10/1

N2 - Condensation of 3-substituted-4-amino-1,2,4-triazole-5-thiones 3 with 3-aryl-sydnone-4-carboxaldehyde 5 afforded a series of Schiff's bases 6. These Schiff's bases underwent Mannich reaction regiospecifically with morpholine and formaldehyde to give Mannich bases 7. The new compounds were characterized by spectral and analytical data. Biological screening results showed promising antibacterial and antifungal activities for these compounds.

AB - Condensation of 3-substituted-4-amino-1,2,4-triazole-5-thiones 3 with 3-aryl-sydnone-4-carboxaldehyde 5 afforded a series of Schiff's bases 6. These Schiff's bases underwent Mannich reaction regiospecifically with morpholine and formaldehyde to give Mannich bases 7. The new compounds were characterized by spectral and analytical data. Biological screening results showed promising antibacterial and antifungal activities for these compounds.

UR - https://www.scopus.com/pages/publications/18244369722

UR - https://www.scopus.com/pages/publications/18244369722#tab=citedBy

M3 - Article

AN - SCOPUS:18244369722

SN - 0971-1627

VL - 14

SP - 127

EP - 130

JO - Indian Journal of Heterocyclic Chemistry

JF - Indian Journal of Heterocyclic Chemistry

IS - 2

ER -

Regiospecific reaction: Synthesis and biological assay of some sydnone and triazole-containing Mannich derivatives

Abstract

All Science Journal Classification (ASJC) codes

Other files and links

Fingerprint

Cite this