Abstract
In this present research program, mucoadhesive polymer tamarind seed polysaccharide (TSP) "galactoxyloglucan" has been used as the drug carrier for delivery systems of anticancer drug, paclitaxel (PTX) with different concentrations for studying the in-vitro drug delivery systems. The structure characterization of polymer-drug composites were investigated by Fourier Transform Infrared Spectra (FTIR), Scanning Electron Microscopy (SEM), Thermogravimetric Analysis (TGA) and X-Ray Diffraction (XRD) Respectively, the drug release was studied by changing time, pH and drug concentrations. The kinetics of the drug release was studied in order to ascertain the type of release mechanism. Based on the diffusion as well as the kinetics, the mechanism of the drug release from the composite matrix has been reported.
| Original language | English |
|---|---|
| Pages (from-to) | 197-206 |
| Number of pages | 10 |
| Journal | European Journal of Scientific Research |
| Volume | 47 |
| Issue number | 2 |
| Publication status | Published - 01-01-2010 |
| Externally published | Yes |
All Science Journal Classification (ASJC) codes
- Computer Science(all)
- Mathematics(all)
- Materials Science(all)
- Agricultural and Biological Sciences(all)
- Engineering(all)
- Earth and Planetary Sciences(all)