TY - JOUR
T1 - Remineralization potential of theobromine on artificial carious lesions
AU - Taneja, Vani
AU - Nekkanti, Sridhar
AU - Gupta, Kanishk
AU - Hassija, Jyoti
N1 - Funding Information:
This study was partially supported by Indian Council of Medical Research, Government of India, New Delhi [grant number 3/2/NOV.2014/PG-THESIS-HRD(23)].
Publisher Copyright:
© 2017 Oxford University Press. All rights reserved.
PY - 2019/11/1
Y1 - 2019/11/1
N2 - Background and Aims: This study aimed to investigate the remineralization potential of two concentrations of theobromine (100 mg/L and 200 mmg/L) with fluoridated dentifrice, NovaMin, and nanohydroxyapatite using DIAGNOdent, scanning electron microscopy (SEM), and energy dispersive X-ray (EDX) analysis. Materials and Methods: Two sections were taken from 50 teeth each. Artificial carious lesions were induced using demineralizing solution. Evaluation using DIAGNOdent, SEM, and EDX analysis for elemental evaluation of Ca/P ratio and fluoride ion was carried out. Teeth sections were then randomly assigned to five different groups: (1) fluoridated dentifrice (ColgateTM, Colgate -Palmolive, India), Novamine- Shy NMTM, Group pharamaceuticals, India), 3. Nano-hydroxyapatite- Remin ProTM, Voco, Germany) 4. 100mg and 5. 200mg of Theobromine toothpaste (Theodent classicTM, Rennou, UK-853069003006). Remineralization was carried out for 14 days with two applications per day. Samples were reanalyzed using DIAGNOdent, SEM, and EDX. Results: A Tukey post-hoc test revealed statistically significant difference between NovaMin and all the other toothpastes (P < 0.001) for DIAGNOdent readings. On performing SEM-EDX analysis, it was seen that all agents had remineralization potential; however, no significant difference was found. Conclusion: Theobromine can be used as an effective novel remineralizing agent alternative to the already-available agents.
AB - Background and Aims: This study aimed to investigate the remineralization potential of two concentrations of theobromine (100 mg/L and 200 mmg/L) with fluoridated dentifrice, NovaMin, and nanohydroxyapatite using DIAGNOdent, scanning electron microscopy (SEM), and energy dispersive X-ray (EDX) analysis. Materials and Methods: Two sections were taken from 50 teeth each. Artificial carious lesions were induced using demineralizing solution. Evaluation using DIAGNOdent, SEM, and EDX analysis for elemental evaluation of Ca/P ratio and fluoride ion was carried out. Teeth sections were then randomly assigned to five different groups: (1) fluoridated dentifrice (ColgateTM, Colgate -Palmolive, India), Novamine- Shy NMTM, Group pharamaceuticals, India), 3. Nano-hydroxyapatite- Remin ProTM, Voco, Germany) 4. 100mg and 5. 200mg of Theobromine toothpaste (Theodent classicTM, Rennou, UK-853069003006). Remineralization was carried out for 14 days with two applications per day. Samples were reanalyzed using DIAGNOdent, SEM, and EDX. Results: A Tukey post-hoc test revealed statistically significant difference between NovaMin and all the other toothpastes (P < 0.001) for DIAGNOdent readings. On performing SEM-EDX analysis, it was seen that all agents had remineralization potential; however, no significant difference was found. Conclusion: Theobromine can be used as an effective novel remineralizing agent alternative to the already-available agents.
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U2 - 10.4103/jispcd.JISPCD_265_19
DO - 10.4103/jispcd.JISPCD_265_19
M3 - Article
AN - SCOPUS:85092341120
SN - 2231-0762
VL - 9
SP - 576
EP - 583
JO - Journal of International Society of Preventive and Community Dentistry
JF - Journal of International Society of Preventive and Community Dentistry
IS - 6
ER -