Retinitis following varicella in a vaccinated child with acute lymphoblastic leukemia

Ashley Ross; Thomas W. McLean; Rebecca Farber; R. Grey Weaver; Allen Chauvenet; Laurence B. Givner; Avinash K. Shetty

doi:10.1002/pbc.20118

Retinitis following varicella in a vaccinated child with acute lymphoblastic leukemia

Ashley Ross, Thomas W. McLean, Rebecca Farber, R. Grey Weaver, Allen Chauvenet, Laurence B. Givner, Avinash K. Shetty^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

Abstract

Serious ocular disease following varicella (chickenpox) is rare in children. In addition, retinitis in children with hematologic malignancies may present a difficult diagnostic challenge because infectious retinitis may mimic leukemic involvement of the eye. We report a 7-year-old patient with T-cell acute lymphoblastic leukemia in remission who presented with visual complaints 2 weeks after developing chickenpox. Ophthalmologic evaluation revealed acute retinitis in the right eye. Prolonged therapy with acyclovir resulted in near complete recovery. Early diagnosis of VZV retinopathy and aggressive antiviral treatment is critical to prevent acute and long-term ocular sequelae.

Original language	English
Pages (from-to)	191-194
Number of pages	4
Journal	Pediatric Blood and Cancer
Volume	45
Issue number	2
DOIs	https://doi.org/10.1002/pbc.20118
Publication status	Published - 01-08-2005
Externally published	Yes

All Science Journal Classification (ASJC) codes

Pediatrics, Perinatology, and Child Health
Hematology
Oncology

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1002/pbc.20118

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title = "Retinitis following varicella in a vaccinated child with acute lymphoblastic leukemia",

abstract = "Serious ocular disease following varicella (chickenpox) is rare in children. In addition, retinitis in children with hematologic malignancies may present a difficult diagnostic challenge because infectious retinitis may mimic leukemic involvement of the eye. We report a 7-year-old patient with T-cell acute lymphoblastic leukemia in remission who presented with visual complaints 2 weeks after developing chickenpox. Ophthalmologic evaluation revealed acute retinitis in the right eye. Prolonged therapy with acyclovir resulted in near complete recovery. Early diagnosis of VZV retinopathy and aggressive antiviral treatment is critical to prevent acute and long-term ocular sequelae.",

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AU - Ross, Ashley

AU - McLean, Thomas W.

AU - Farber, Rebecca

AU - Weaver, R. Grey

AU - Chauvenet, Allen

AU - Givner, Laurence B.

AU - Shetty, Avinash K.

PY - 2005/8/1

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AB - Serious ocular disease following varicella (chickenpox) is rare in children. In addition, retinitis in children with hematologic malignancies may present a difficult diagnostic challenge because infectious retinitis may mimic leukemic involvement of the eye. We report a 7-year-old patient with T-cell acute lymphoblastic leukemia in remission who presented with visual complaints 2 weeks after developing chickenpox. Ophthalmologic evaluation revealed acute retinitis in the right eye. Prolonged therapy with acyclovir resulted in near complete recovery. Early diagnosis of VZV retinopathy and aggressive antiviral treatment is critical to prevent acute and long-term ocular sequelae.

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Retinitis following varicella in a vaccinated child with acute lymphoblastic leukemia

Abstract

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