Retinitis following varicella in a vaccinated child with acute lymphoblastic leukemia

Ashley Ross; Thomas W. McLean; Rebecca Farber; R. Grey Weaver; Allen Chauvenet; Laurence B. Givner; Avinash K. Shetty

doi:10.1002/pbc.20118

Retinitis following varicella in a vaccinated child with acute lymphoblastic leukemia

Ashley Ross
, Thomas W. McLean
, Rebecca Farber
, R. Grey Weaver
, Allen Chauvenet
, Laurence B. Givner
, Avinash K. Shetty^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

Abstract

Serious ocular disease following varicella (chickenpox) is rare in children. In addition, retinitis in children with hematologic malignancies may present a difficult diagnostic challenge because infectious retinitis may mimic leukemic involvement of the eye. We report a 7-year-old patient with T-cell acute lymphoblastic leukemia in remission who presented with visual complaints 2 weeks after developing chickenpox. Ophthalmologic evaluation revealed acute retinitis in the right eye. Prolonged therapy with acyclovir resulted in near complete recovery. Early diagnosis of VZV retinopathy and aggressive antiviral treatment is critical to prevent acute and long-term ocular sequelae.

Original language	English
Pages (from-to)	191-194
Number of pages	4
Journal	Pediatric Blood and Cancer
Volume	45
Issue number	2
DOIs	https://doi.org/10.1002/pbc.20118
Publication status	Published - 01-08-2005
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

All Science Journal Classification (ASJC) codes

Pediatrics, Perinatology, and Child Health
Hematology
Oncology

Access to Document

10.1002/pbc.20118

Cite this

@article{9c4e40684c504584983993640a491dbc,

title = "Retinitis following varicella in a vaccinated child with acute lymphoblastic leukemia",

abstract = "Serious ocular disease following varicella (chickenpox) is rare in children. In addition, retinitis in children with hematologic malignancies may present a difficult diagnostic challenge because infectious retinitis may mimic leukemic involvement of the eye. We report a 7-year-old patient with T-cell acute lymphoblastic leukemia in remission who presented with visual complaints 2 weeks after developing chickenpox. Ophthalmologic evaluation revealed acute retinitis in the right eye. Prolonged therapy with acyclovir resulted in near complete recovery. Early diagnosis of VZV retinopathy and aggressive antiviral treatment is critical to prevent acute and long-term ocular sequelae.",

author = "Ashley Ross and McLean, \{Thomas W.\} and Rebecca Farber and Weaver, \{R. Grey\} and Allen Chauvenet and Givner, \{Laurence B.\} and Shetty, \{Avinash K.\}",

year = "2005",

month = aug,

day = "1",

doi = "10.1002/pbc.20118",

language = "English",

volume = "45",

pages = "191--194",

journal = "Pediatric Blood and Cancer",

issn = "1545-5009",

publisher = "Wiley-Liss Inc.",

number = "2",

}

TY - JOUR

T1 - Retinitis following varicella in a vaccinated child with acute lymphoblastic leukemia

AU - Ross, Ashley

AU - McLean, Thomas W.

AU - Farber, Rebecca

AU - Weaver, R. Grey

AU - Chauvenet, Allen

AU - Givner, Laurence B.

AU - Shetty, Avinash K.

PY - 2005/8/1

Y1 - 2005/8/1

N2 - Serious ocular disease following varicella (chickenpox) is rare in children. In addition, retinitis in children with hematologic malignancies may present a difficult diagnostic challenge because infectious retinitis may mimic leukemic involvement of the eye. We report a 7-year-old patient with T-cell acute lymphoblastic leukemia in remission who presented with visual complaints 2 weeks after developing chickenpox. Ophthalmologic evaluation revealed acute retinitis in the right eye. Prolonged therapy with acyclovir resulted in near complete recovery. Early diagnosis of VZV retinopathy and aggressive antiviral treatment is critical to prevent acute and long-term ocular sequelae.

AB - Serious ocular disease following varicella (chickenpox) is rare in children. In addition, retinitis in children with hematologic malignancies may present a difficult diagnostic challenge because infectious retinitis may mimic leukemic involvement of the eye. We report a 7-year-old patient with T-cell acute lymphoblastic leukemia in remission who presented with visual complaints 2 weeks after developing chickenpox. Ophthalmologic evaluation revealed acute retinitis in the right eye. Prolonged therapy with acyclovir resulted in near complete recovery. Early diagnosis of VZV retinopathy and aggressive antiviral treatment is critical to prevent acute and long-term ocular sequelae.

UR - https://www.scopus.com/pages/publications/22244474653

UR - https://www.scopus.com/pages/publications/22244474653#tab=citedBy

U2 - 10.1002/pbc.20118

DO - 10.1002/pbc.20118

M3 - Article

C2 - 15880424

AN - SCOPUS:22244474653

SN - 1545-5009

VL - 45

SP - 191

EP - 194

JO - Pediatric Blood and Cancer

JF - Pediatric Blood and Cancer

IS - 2

ER -

Retinitis following varicella in a vaccinated child with acute lymphoblastic leukemia

Abstract

UN SDGs

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this