Review-Thin-Film Transistors (TFTs) for Highly Sensitive Biosensing Applications: A Review

This review manuscript presents Thin-Film Transistors (TFTs) for various highly sensitive biosensing applications. A low-cost, highly sensitive, early-stage diagnostic bio-sensing devices are vital for different biomedical and biological applications. Nanotechnology-based biosensor devices such as bioFET, thin-film transistor (TFT), etc. are used to overcome the problems of conventional health diagnostic approaches. Among them, TFT based biosensors have gained a lot of attention owing to high sensitivity, high-scalability, low power consumption, rapid electrical detection, low-cost mass production, and direct electrical readouts. Further to improve the sensitivity of TFT bases biosensor, transparent materials are frequently used in current biosensing research fields and it is found that indium tin oxide (ITO) is most favorable for biosensing applications. Thus, the amalgamation of ITO on TFT paves the way with the existing CMOS technology for early-stage diagnostic of protein-related diseases such as coronary artery disease, ovarian cancer, and Alzheimer's diseases.