Role of prebiotic dietary fiber in periodontal disease: A systematic review of animal studies

Rohan Tailor, Nidhi Medara, Aditi Chopra, Hasinthi Swarnamali, Joerg Eberhard, Thilini N. Jayasinghe

Research output: Contribution to journalReview articlepeer-review


Background: Periodontitis is a chronic inflammatory condition affecting the supporting structures of a tooth in the oral cavity. The relationship between dietary fiber and periodontitis is poorly understood. The objective of this systematic review is to investigate if an intake of dietary fiber modulates periodontal disease in animal models and any concomitant effects on systemic inflammation, microbiota and their metabolites. Methods: Animal studies using periodontitis models with any form of fiber intervention were included. Studies with comorbidities that were mutually inclusive with periodontitis and animals with physiological conditions were excluded. Search strategy with MeSH and free-text search terms were finalized and performed on the 22nd of September 2021.CINAHL Complete, EMBASE, MEDLINE, SciVerse Scopus® and Web of Science Core Collection databases were used to identify studies. SYRCLE’s risk of bias tool and CAMARADES were used for quality assessment.

Original languageEnglish
Article number1130153
JournalFrontiers in Nutrition
Publication statusPublished - 2023

All Science Journal Classification (ASJC) codes

  • Food Science
  • Endocrinology, Diabetes and Metabolism
  • Nutrition and Dietetics


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