Role of Vitamin D and antioxidants in the prevention and treatment of Alzheimer's disease

Shilia Jacob Kurian*, Ruby Benson, Sonal Sekhar Miraj, Mahadev Rao

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

The free radicals and neuroinflammatory processes are thought to underlie various neurodegenerative diseases such as Alzheimer's disease (AD) as the brain is highly susceptible to oxidative damage. Docosahexaenoic acid, choline, folate, vitamin B12, vitamin C, vitamin E, and copper were found to be significantly lower in the brain of AD patients. Nutritional therapy, which includes vitamin D and other antioxidants, has shown a potential effect in the prevention and treatment of AD through acting on various biological pathways. Nutrition is an essential lifestyle factor that can modify the risk of several neurodegenerative disorders. The free radicals and neuroinflammatory processes are thought to underlie various neurodegenerative diseases such as Alzheimer's disease as the brain is highly susceptible to oxidative damage. Prevention of dementia is a major concern as there exists a lack of a permanent cure. The Food and Nutrition Board at the Institute of Medicine of the National Academies has been given the Recommended Dietary Allowance of vitamin D.

Original languageEnglish
Title of host publicationAntioxidants and Functional Foods for Neurodegenerative Disorders
Subtitle of host publicationUses in Prevention and Therapy
PublisherCRC Press
Pages185-201
Number of pages17
ISBN (Electronic)9780429319310
ISBN (Print)9780367333225
Publication statusPublished - 07-01-2021

All Science Journal Classification (ASJC) codes

  • General Health Professions
  • General Medicine
  • General Biochemistry,Genetics and Molecular Biology
  • General Agricultural and Biological Sciences

Fingerprint

Dive into the research topics of 'Role of Vitamin D and antioxidants in the prevention and treatment of Alzheimer's disease'. Together they form a unique fingerprint.

Cite this