Rosette-forming glioneuronal tumor - Evidence of stem cell origin with biphenotypic differentiation

S. Chakraborti; A. Mahadevan; A. Govindan; A. Bhateja; S. Dwarakanath; H. R. Aravinda; A. A. Phalguni; V. Santosh; T. C. Yasha; P. Rout; S. Sampath; S. K. Shankar

doi:10.1007/s00428-012-1313-0

Rosette-forming glioneuronal tumor - Evidence of stem cell origin with biphenotypic differentiation

S. Chakraborti, A. Mahadevan, A. Govindan, A. Bhateja, S. Dwarakanath, H. R. Aravinda, A. A. Phalguni, V. Santosh, T. C. Yasha, P. Rout, S. Sampath, S. K. Shankar

Department of Pathology, Kasturba Medical College, Mangalore

Research output: Contribution to journal › Article › peer-review

16 Citations (Scopus)

Abstract

Rosette-forming glioneuronal tumor (RGNT) of the fourth ventricle is a new addition to the WHO classification of central nervous system tumors. To date, 72 cases have been described in literature. In the present study, we report the clinical and imaging features, with detailed histopathological and immunohistochemical profile, of eight cases. Confocal microscopic evidence of stem cell origin with biphenotypic, glial and neurocytic differentiation is presented with a comprehensive review of literature.

Original language	English
Pages (from-to)	581-588
Number of pages	8
Journal	Virchows Archiv
Volume	461
Issue number	5
DOIs	https://doi.org/10.1007/s00428-012-1313-0
Publication status	Published - 01-11-2012

All Science Journal Classification (ASJC) codes

Pathology and Forensic Medicine
Molecular Biology
Cell Biology

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abstract = "Rosette-forming glioneuronal tumor (RGNT) of the fourth ventricle is a new addition to the WHO classification of central nervous system tumors. To date, 72 cases have been described in literature. In the present study, we report the clinical and imaging features, with detailed histopathological and immunohistochemical profile, of eight cases. Confocal microscopic evidence of stem cell origin with biphenotypic, glial and neurocytic differentiation is presented with a comprehensive review of literature.",

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AU - Chakraborti, S.

AU - Mahadevan, A.

AU - Govindan, A.

AU - Bhateja, A.

AU - Dwarakanath, S.

AU - Aravinda, H. R.

AU - Phalguni, A. A.

AU - Santosh, V.

AU - Yasha, T. C.

AU - Rout, P.

AU - Sampath, S.

AU - Shankar, S. K.

PY - 2012/11/1

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AB - Rosette-forming glioneuronal tumor (RGNT) of the fourth ventricle is a new addition to the WHO classification of central nervous system tumors. To date, 72 cases have been described in literature. In the present study, we report the clinical and imaging features, with detailed histopathological and immunohistochemical profile, of eight cases. Confocal microscopic evidence of stem cell origin with biphenotypic, glial and neurocytic differentiation is presented with a comprehensive review of literature.

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Rosette-forming glioneuronal tumor - Evidence of stem cell origin with biphenotypic differentiation

Abstract

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