Scaffold modification and synthesis routes for targeting mutant IDH 1: a review

INIS

• reviews 100%
• modifications 100%
• synthesis 100%
• mutants 100%
• drugs 50%
• cancer 50%
• gliomas 50%
• blood-brain barrier 50%
• metabolites 50%
• stability 50%
• optimization 50%
• quinolines 50%
• pyrazoles 50%
• coupling 50%
• palladium 50%
• heterocyclic compounds 50%
• triazines 50%

Pharmacology, Toxicology and Pharmaceutical Science

• Vorasidenib 100%
• Ivosidenib 100%