TY - JOUR
T1 - Sedentarism and chronic disease risk in COVID 19 lockdown – a scoping review
AU - Chandrasekaran, Baskaran
AU - Ganesan, Thiru Balaji
PY - 2021/2
Y1 - 2021/2
N2 - Background & Aims: Though viewed as a critical measure to prevent the spread of the virus, a prolonged homestay may result in unfavourable sedentary behaviour and chronic disease risk. This systematic review focuses on sedentary behaviour resulting from this quarantine period which may elevate the cardiovascular disease risk, obesity, hypertension, cancer and mental health illness. Methods: Evidence of breaking sedentary behaviour and global recommendations were investigated. Potential unanswered questions regarding sedentary behaviour and physical activity during lockdown were explored. Results: Five systematic reviews and six prospective trials explored the effect of sedentarism affecting chronic disease through potential pathophysiological mechanisms. Sedentary behaviour especially prolonged sitting is found to be a pleiotropic risk factor with altered energy expenditure, adipogenic signalling, immunomodulation, autonomic stability and hormonal dysregulation perpetuating underlying chronic diseases such as obesity, cardiovascular disease, cancer and mental health disorders. Conclusion: Breaking sitting and physical activity are found to reverse the adverse effects associated with excessive sitting during the lockdown.
AB - Background & Aims: Though viewed as a critical measure to prevent the spread of the virus, a prolonged homestay may result in unfavourable sedentary behaviour and chronic disease risk. This systematic review focuses on sedentary behaviour resulting from this quarantine period which may elevate the cardiovascular disease risk, obesity, hypertension, cancer and mental health illness. Methods: Evidence of breaking sedentary behaviour and global recommendations were investigated. Potential unanswered questions regarding sedentary behaviour and physical activity during lockdown were explored. Results: Five systematic reviews and six prospective trials explored the effect of sedentarism affecting chronic disease through potential pathophysiological mechanisms. Sedentary behaviour especially prolonged sitting is found to be a pleiotropic risk factor with altered energy expenditure, adipogenic signalling, immunomodulation, autonomic stability and hormonal dysregulation perpetuating underlying chronic diseases such as obesity, cardiovascular disease, cancer and mental health disorders. Conclusion: Breaking sitting and physical activity are found to reverse the adverse effects associated with excessive sitting during the lockdown.
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U2 - 10.1177/0036933020946336
DO - 10.1177/0036933020946336
M3 - Article
C2 - 32718266
AN - SCOPUS:85088842133
SN - 0036-9330
VL - 66
SP - 3
EP - 10
JO - Scottish Medical Journal
JF - Scottish Medical Journal
IS - 1
ER -