TY - JOUR
T1 - Semen quality and age-specific changes
T2 - A study between two decades on 3,729 male partners of couples with normal sperm count and attending an andrology laboratory for infertility-related problems in an Indian city
AU - Mukhopadhyay, Dyutiman
AU - Varghese, Alex C.
AU - Pal, Manisha
AU - Banerjee, Sudip K.
AU - Bhattacharyya, Asok K.
AU - Sharma, Rakesh K.
AU - Agarwal, Ashok
PY - 2010/5/1
Y1 - 2010/5/1
N2 - Objective: To compare the semen quality and age-specific changes in men between the 1980s and 2000s. Design: Prospective study. Setting: Andrology laboratory, University of Calcutta, India. Patient(s): A semen sample was obtained from 3729 men presenting for infertility problems in two distinct decades, that is, between 1981-85 and 2000-2006. Intervention(s): Subjects with sperm count >20 × 106/mL without any extreme pathological disorders were selected. Samples having a major liquefaction problem were excluded. Main Outcome Measure(s): A standard World Health Organization procedure for semen analysis was performed that included assessment of volume, sperm concentration, and percentage motility. The motility parameters were further classified into forward progressive motility and nonprogressive motility. Result(s): The present large-scale study confirms a significant decline in the sperm motility parameters and seminal volume in the present decade. However, no change in overall sperm concentration was noted. A decline was seen in sperm motility with increasing age in both decades. Conclusion(s): There are significant changes in sperm motility and volume between the two decades, and the agerelated changes in semen parameters are also different in the two decades.
AB - Objective: To compare the semen quality and age-specific changes in men between the 1980s and 2000s. Design: Prospective study. Setting: Andrology laboratory, University of Calcutta, India. Patient(s): A semen sample was obtained from 3729 men presenting for infertility problems in two distinct decades, that is, between 1981-85 and 2000-2006. Intervention(s): Subjects with sperm count >20 × 106/mL without any extreme pathological disorders were selected. Samples having a major liquefaction problem were excluded. Main Outcome Measure(s): A standard World Health Organization procedure for semen analysis was performed that included assessment of volume, sperm concentration, and percentage motility. The motility parameters were further classified into forward progressive motility and nonprogressive motility. Result(s): The present large-scale study confirms a significant decline in the sperm motility parameters and seminal volume in the present decade. However, no change in overall sperm concentration was noted. A decline was seen in sperm motility with increasing age in both decades. Conclusion(s): There are significant changes in sperm motility and volume between the two decades, and the agerelated changes in semen parameters are also different in the two decades.
UR - https://www.scopus.com/pages/publications/77952566281
UR - https://www.scopus.com/pages/publications/77952566281#tab=citedBy
U2 - 10.1016/j.fertnstert.2009.01.135
DO - 10.1016/j.fertnstert.2009.01.135
M3 - Article
C2 - 19328484
AN - SCOPUS:77952566281
SN - 0015-0282
VL - 93
SP - 2247
EP - 2254
JO - Fertility and Sterility
JF - Fertility and Sterility
IS - 7
ER -