Serum glycoconjugates and ceruloplasmin in cancer of uterine cervix

Sharmila Upadhya; Subramanya Upadhya; K. S. Prabhu

doi:10.1007/BF02867936

Serum glycoconjugates and ceruloplasmin in cancer of uterine cervix

Sharmila Upadhya, Subramanya Upadhya, K. S. Prabhu

Research output: Contribution to journal › Article › peer-review

13 Citations (Scopus)

Abstract

The present study was done to assess the levels of glycoconjugates and ceruloplasmin in sera of patients with cervical cancer. Serum hexoses, hexosamines, sialic acid and fucose are elevated in a variety of inflammatory and neoplastic conditions. All the glycoconjugates, except fucose were increased in serum of patients compared to controls. Also, hexoses and sialic acid levels were high in patients with later stages of cancer compared to patients with early stage disease (P=<0.0001,P=0.03). Serum ceruloplasmin was increased in patients with early stage cancer (51.5mg/dl) and with late stage cancer (61mg/dl) compared to controls (38mg/dl). The elevated glycoconjugates may be the result of inflammatory reaction associated with neoplasia, as serum ceruloplasmin (an acute phase reactant) is also increased in these patients.

Original language	English
Pages (from-to)	20-24
Number of pages	5
Journal	Indian Journal of Clinical Biochemistry
Volume	17
Issue number	1
DOIs	https://doi.org/10.1007/BF02867936
Publication status	Published - 01-01-2002
Externally published	Yes

All Science Journal Classification (ASJC) codes

Clinical Biochemistry

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1007/BF02867936

Cite this

@article{a65207ba576941a884ff330308fb7c82,

title = "Serum glycoconjugates and ceruloplasmin in cancer of uterine cervix",

abstract = "The present study was done to assess the levels of glycoconjugates and ceruloplasmin in sera of patients with cervical cancer. Serum hexoses, hexosamines, sialic acid and fucose are elevated in a variety of inflammatory and neoplastic conditions. All the glycoconjugates, except fucose were increased in serum of patients compared to controls. Also, hexoses and sialic acid levels were high in patients with later stages of cancer compared to patients with early stage disease (P=<0.0001,P=0.03). Serum ceruloplasmin was increased in patients with early stage cancer (51.5mg/dl) and with late stage cancer (61mg/dl) compared to controls (38mg/dl). The elevated glycoconjugates may be the result of inflammatory reaction associated with neoplasia, as serum ceruloplasmin (an acute phase reactant) is also increased in these patients.",

author = "Sharmila Upadhya and Subramanya Upadhya and Prabhu, {K. S.}",

year = "2002",

month = jan,

day = "1",

doi = "10.1007/BF02867936",

language = "English",

volume = "17",

pages = "20--24",

journal = "Indian Journal of Clinical Biochemistry",

issn = "0970-1915",

publisher = "Springer India",

number = "1",

}

TY - JOUR

T1 - Serum glycoconjugates and ceruloplasmin in cancer of uterine cervix

AU - Upadhya, Sharmila

AU - Upadhya, Subramanya

AU - Prabhu, K. S.

PY - 2002/1/1

Y1 - 2002/1/1

N2 - The present study was done to assess the levels of glycoconjugates and ceruloplasmin in sera of patients with cervical cancer. Serum hexoses, hexosamines, sialic acid and fucose are elevated in a variety of inflammatory and neoplastic conditions. All the glycoconjugates, except fucose were increased in serum of patients compared to controls. Also, hexoses and sialic acid levels were high in patients with later stages of cancer compared to patients with early stage disease (P=<0.0001,P=0.03). Serum ceruloplasmin was increased in patients with early stage cancer (51.5mg/dl) and with late stage cancer (61mg/dl) compared to controls (38mg/dl). The elevated glycoconjugates may be the result of inflammatory reaction associated with neoplasia, as serum ceruloplasmin (an acute phase reactant) is also increased in these patients.

AB - The present study was done to assess the levels of glycoconjugates and ceruloplasmin in sera of patients with cervical cancer. Serum hexoses, hexosamines, sialic acid and fucose are elevated in a variety of inflammatory and neoplastic conditions. All the glycoconjugates, except fucose were increased in serum of patients compared to controls. Also, hexoses and sialic acid levels were high in patients with later stages of cancer compared to patients with early stage disease (P=<0.0001,P=0.03). Serum ceruloplasmin was increased in patients with early stage cancer (51.5mg/dl) and with late stage cancer (61mg/dl) compared to controls (38mg/dl). The elevated glycoconjugates may be the result of inflammatory reaction associated with neoplasia, as serum ceruloplasmin (an acute phase reactant) is also increased in these patients.

UR - http://www.scopus.com/inward/record.url?scp=33645492015&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33645492015&partnerID=8YFLogxK

U2 - 10.1007/BF02867936

DO - 10.1007/BF02867936

M3 - Article

AN - SCOPUS:33645492015

SN - 0970-1915

VL - 17

SP - 20

EP - 24

JO - Indian Journal of Clinical Biochemistry

JF - Indian Journal of Clinical Biochemistry

IS - 1

ER -

Serum glycoconjugates and ceruloplasmin in cancer of uterine cervix

Abstract

All Science Journal Classification (ASJC) codes

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this