TY - JOUR
T1 - Serum Lactate Dehydrogenase in Non-Hodgkin’s Lymphoma
T2 - A Prognostic Indicator
AU - Yadav, Charu
AU - Ahmad, Afzal
AU - D’Souza, Benedicta
AU - Agarwal, Ashish
AU - Nandini, M.
AU - Ashok Prabhu, K.
AU - D’Souza, Vivian
N1 - Publisher Copyright:
© 2015, Association of Clinical Biochemists of India.
PY - 2016/4/1
Y1 - 2016/4/1
N2 - Non-Hodgkin’s lymphoma constitutes a group of disorders originating from the malignant transformation of lymphocytes and involving either the lymph nodes or extranodal sites. NHL commonly presents in the sixth to seventh decade of life with a male preponderance (50–75 %). Recent studies have shown importance of serum LDH in prognosis of NHL. Authors report a case of a 63 year old male presenting with complaints of fever and backache for past 4 months. General and systemic examination revealed bilateral axillary lymphadenopathy and splenomegaly respectively. Serum LDH level was highly elevated (3441 U/l). Excisional axillary and bone marrow biopsy were done before oncology referral. Complete workup revealed diffuse Non-Hodgkin’s lymphoma with bone marrow infiltration. Patient died because of acute renal failure due to NHL and DM 2 (Type 2 diabetes mellitus).
AB - Non-Hodgkin’s lymphoma constitutes a group of disorders originating from the malignant transformation of lymphocytes and involving either the lymph nodes or extranodal sites. NHL commonly presents in the sixth to seventh decade of life with a male preponderance (50–75 %). Recent studies have shown importance of serum LDH in prognosis of NHL. Authors report a case of a 63 year old male presenting with complaints of fever and backache for past 4 months. General and systemic examination revealed bilateral axillary lymphadenopathy and splenomegaly respectively. Serum LDH level was highly elevated (3441 U/l). Excisional axillary and bone marrow biopsy were done before oncology referral. Complete workup revealed diffuse Non-Hodgkin’s lymphoma with bone marrow infiltration. Patient died because of acute renal failure due to NHL and DM 2 (Type 2 diabetes mellitus).
UR - https://www.scopus.com/pages/publications/84931864128
UR - https://www.scopus.com/pages/publications/84931864128#tab=citedBy
U2 - 10.1007/s12291-015-0511-3
DO - 10.1007/s12291-015-0511-3
M3 - Article
AN - SCOPUS:84931864128
SN - 0970-1915
VL - 31
SP - 240
EP - 242
JO - Indian Journal of Clinical Biochemistry
JF - Indian Journal of Clinical Biochemistry
IS - 2
ER -
