Significance of lymphocytic sister chromatid exchange frequencies in ovarian cancer patients

Pawan Kumar Dhar; Sulochna Devi; T. Ramesh Rao; Usha Kumari; Anita Joseph; M. R. Kumar; Satish Nayak; Y. Shreemati; S. M. Bhat; K. R. Bhat

doi:10.1016/0165-4608(95)00071-2

Significance of lymphocytic sister chromatid exchange frequencies in ovarian cancer patients

Pawan Kumar Dhar
, Sulochna Devi
, T. Ramesh Rao
, Usha Kumari
, Anita Joseph
, M. R. Kumar
, Satish Nayak
, Y. Shreemati
, S. M. Bhat
, K. R. Bhat

Research output: Contribution to journal › Article › peer-review

17 Citations (Scopus)

Abstract

Very few studies report the analysis of sister chromatid exchanges in ovarian cancer patients. We tested the null hypothesis that SCE frequency increases with the advancing stages of ovarian cancer and follows a Poisson distribution. As controls we examined age- and sex-matched healthy volunteers who had no such past history. An increased average SCE frequency was observed in ovarian cancer patients (6.34 ± 0.09) vis-a-vis controls (4.47 ± 0.12). Further, the data also suggested a stage-wise increase in the SCE frequency.

Original language	English
Pages (from-to)	105-108
Number of pages	4
Journal	Cancer Genetics and Cytogenetics
Volume	89
Issue number	2
DOIs	https://doi.org/10.1016/0165-4608(95)00071-2
Publication status	Published - 15-07-1996
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

All Science Journal Classification (ASJC) codes

Molecular Biology
Genetics
Cancer Research

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10.1016/0165-4608(95)00071-2

Cite this

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title = "Significance of lymphocytic sister chromatid exchange frequencies in ovarian cancer patients",

abstract = "Very few studies report the analysis of sister chromatid exchanges in ovarian cancer patients. We tested the null hypothesis that SCE frequency increases with the advancing stages of ovarian cancer and follows a Poisson distribution. As controls we examined age- and sex-matched healthy volunteers who had no such past history. An increased average SCE frequency was observed in ovarian cancer patients (6.34 ± 0.09) vis-a-vis controls (4.47 ± 0.12). Further, the data also suggested a stage-wise increase in the SCE frequency.",

author = "\{Kumar Dhar\}, Pawan and Sulochna Devi and \{Ramesh Rao\}, T. and Usha Kumari and Anita Joseph and Kumar, \{M. R.\} and Satish Nayak and Y. Shreemati and Bhat, \{S. M.\} and Bhat, \{K. R.\}",

year = "1996",

month = jul,

day = "15",

doi = "10.1016/0165-4608(95)00071-2",

language = "English",

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journal = "Cancer Genetics and Cytogenetics",

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T1 - Significance of lymphocytic sister chromatid exchange frequencies in ovarian cancer patients

AU - Kumar Dhar, Pawan

AU - Devi, Sulochna

AU - Ramesh Rao, T.

AU - Kumari, Usha

AU - Joseph, Anita

AU - Kumar, M. R.

AU - Nayak, Satish

AU - Shreemati, Y.

AU - Bhat, S. M.

AU - Bhat, K. R.

PY - 1996/7/15

Y1 - 1996/7/15

N2 - Very few studies report the analysis of sister chromatid exchanges in ovarian cancer patients. We tested the null hypothesis that SCE frequency increases with the advancing stages of ovarian cancer and follows a Poisson distribution. As controls we examined age- and sex-matched healthy volunteers who had no such past history. An increased average SCE frequency was observed in ovarian cancer patients (6.34 ± 0.09) vis-a-vis controls (4.47 ± 0.12). Further, the data also suggested a stage-wise increase in the SCE frequency.

AB - Very few studies report the analysis of sister chromatid exchanges in ovarian cancer patients. We tested the null hypothesis that SCE frequency increases with the advancing stages of ovarian cancer and follows a Poisson distribution. As controls we examined age- and sex-matched healthy volunteers who had no such past history. An increased average SCE frequency was observed in ovarian cancer patients (6.34 ± 0.09) vis-a-vis controls (4.47 ± 0.12). Further, the data also suggested a stage-wise increase in the SCE frequency.

UR - https://www.scopus.com/pages/publications/0004467515

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U2 - 10.1016/0165-4608(95)00071-2

DO - 10.1016/0165-4608(95)00071-2

M3 - Article

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AN - SCOPUS:0004467515

SN - 0165-4608

VL - 89

SP - 105

EP - 108

JO - Cancer Genetics and Cytogenetics

JF - Cancer Genetics and Cytogenetics

IS - 2

ER -

Significance of lymphocytic sister chromatid exchange frequencies in ovarian cancer patients

Abstract

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