Sjogren's syndrome: A review

Sjogren's syndrome is a slowly progressive, inflammatory autoimmune disease affecting primarily the exocrine glands like lacrimal and salivary glands. Histologically, it is characterised by lymphocytic infiltrates that replace functional epithelium and lead to decreased exocrine secretions. The various clinical features of Sjogren's syndrome are keratitis, xerostomia and salivary gland enlargement. The condition can be diagnosed by various methods like Schirmer test, sialography, biopsy, etc. and can be treated accordingly.