Spatially controlled DNA unzipping by microfluidic interface positioning on a molecule perpendicular to a multicomponent flow

Naresh K. Mani; Sergii Rudiuk; Damien Baigl

doi:10.1039/c3cc44016h

Spatially controlled DNA unzipping by microfluidic interface positioning on a molecule perpendicular to a multicomponent flow

Naresh K. Mani, Sergii Rudiuk, Damien Baigl

Research output: Contribution to journal › Article › peer-review

15 Citations (Scopus)

Abstract

A DNA molecule is rotated under a transversal electric field to be perpendicular to a longitudinal, multicomponent microfluidic flow. Positioning the interface allows us to control DNA unzipping with spatio-temporal resolution. This demonstrates that a microfluidic gradient can be applied at the single molecule level for a dynamic intramolecular stimulation.

Original language	English
Pages (from-to)	6858-6860
Number of pages	3
Journal	Chemical Communications
Volume	49
Issue number	61
DOIs	https://doi.org/10.1039/c3cc44016h
Publication status	Published - 07-08-2013

All Science Journal Classification (ASJC) codes

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
Chemistry(all)
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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10.1039/c3cc44016h

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abstract = "A DNA molecule is rotated under a transversal electric field to be perpendicular to a longitudinal, multicomponent microfluidic flow. Positioning the interface allows us to control DNA unzipping with spatio-temporal resolution. This demonstrates that a microfluidic gradient can be applied at the single molecule level for a dynamic intramolecular stimulation.",

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Spatially controlled DNA unzipping by microfluidic interface positioning on a molecule perpendicular to a multicomponent flow

Abstract

All Science Journal Classification (ASJC) codes

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