Spectroscopic and histological evaluation of wound healing progression following Low Level Laser Therapy (LLLT)

Vijendra Prabhu; Satish B.S. Rao; Subhash Chandra; Pramod Kumar; Lakshmi Rao; Vasudeva Guddattu; Kapaettu Satyamoorthy; Krishna K. Mahato

doi:10.1002/jbio.201100089

Spectroscopic and histological evaluation of wound healing progression following Low Level Laser Therapy (LLLT)

Vijendra Prabhu, Satish B.S. Rao, Subhash Chandra, Pramod Kumar, Lakshmi Rao, Vasudeva Guddattu, Kapaettu Satyamoorthy, Krishna K. Mahato

Research output: Contribution to journal › Article › peer-review

49 Citations (Scopus)

Abstract

The present study focuses on the evaluation of the effect of He-Ne laser on tissue regeneration by monitoring collagen synthesis in wound granulation tissues in Swiss albino mice using analysis of laser induced fluorescence (LIF) and light microscopy techniques. The spectral analyses of the wound granulation tissues have indicated a dose dependent increase in collagen levels during the post-wounding days. The histological examinations on the other hand have also shown a significant increase in collagen deposition along with the reduced edema, leukocytes, increased granulation tissue, and fibroblast number in the optimal laser dose treated group compared to the non-illuminated controls.

Original language	English
Pages (from-to)	168-184
Number of pages	17
Journal	Journal of Biophotonics
Volume	5
Issue number	2
DOIs	https://doi.org/10.1002/jbio.201100089
Publication status	Published - 02-2012

All Science Journal Classification (ASJC) codes

Chemistry(all)
Materials Science(all)
Biochemistry, Genetics and Molecular Biology(all)
Engineering(all)
Physics and Astronomy(all)

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10.1002/jbio.201100089

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title = "Spectroscopic and histological evaluation of wound healing progression following Low Level Laser Therapy (LLLT)",

abstract = "The present study focuses on the evaluation of the effect of He-Ne laser on tissue regeneration by monitoring collagen synthesis in wound granulation tissues in Swiss albino mice using analysis of laser induced fluorescence (LIF) and light microscopy techniques. The spectral analyses of the wound granulation tissues have indicated a dose dependent increase in collagen levels during the post-wounding days. The histological examinations on the other hand have also shown a significant increase in collagen deposition along with the reduced edema, leukocytes, increased granulation tissue, and fibroblast number in the optimal laser dose treated group compared to the non-illuminated controls.",

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AU - Prabhu, Vijendra

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AU - Chandra, Subhash

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AU - Rao, Lakshmi

AU - Guddattu, Vasudeva

AU - Satyamoorthy, Kapaettu

AU - Mahato, Krishna K.

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Spectroscopic and histological evaluation of wound healing progression following Low Level Laser Therapy (LLLT)

Abstract

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