Spontaneous capsular ruptures in Alport syndrome

Alport syndrome is an inherited disorder affecting the basement membranes, predominantly of the kidneys, eyes, and ears. In our series of 8 patients, anterior lenticonus was the most common ocular feature, as is typical in these cases. However, spontaneous capsular rupture was the presenting feature in 3 patients, rarely reported in Alport syndrome. On follow-up (3 months), all had spontaneous rupture of the lenticonus in the other eye.