Sporadic Creutzfeldt-Jakob disease-A review

Stuti Sharma, Madhurima Mukherjee, Vivekananda Kedage, Manjunatha S. Muttigi, Anjali Rao, Suryanarayana Rao

Research output: Contribution to journalArticlepeer-review

14 Citations (Scopus)


The objective is to study a patient with sporadic CreutzfeldtJakob disease (CJD). The patient, a 70-year-old woman with a history spanning over 1 month, with acute onset, progressive abnormal behavior, and cognitive decline with generalized asymmetrical myoclonic jerking, startle phenomenon, and cortical blindness, was referred to the hospital. On observation of clinical symptoms, metabolic and hematological investigations, MRI (magnetic resonance imaging), and EEG (electroencephalogram) were done. The clinical symptoms, MRI, and diagnostic EEG were suggestive of sporadic CJD. Other metabolic encephalopathies were ruled out. With sodium valproate and clonezepam, her myoclonic jerks improved slightly. As CJD is an incurable disease, no definitive treatment could be given.

Original languageEnglish
Pages (from-to)1981-1994
Number of pages14
JournalInternational Journal of Neuroscience
Issue number11
Publication statusPublished - 22-10-2009

All Science Journal Classification (ASJC) codes

  • Neuroscience(all)


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