TY - JOUR
T1 - Stability indicating HPLC method for venlafaxine hydrochloride capsules
AU - Vijayaraghavan, R.
AU - Radha, S.
AU - Shenoy Gautham, G.
AU - Jain, S.
AU - Vaidya, L.
AU - Ahmad, F.
N1 - Export Date: 10 November 2017
CODEN: AJCHE
Correspondence Address: Radha, S.; School of Studies in Pharmaceutical Sciences, Jiwaji University, Gwalior-474 011, India; email: [email protected]
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PY - 2008
Y1 - 2008
N2 - A stability indicating HPLC method for the analysis of venlafaxine hydrochloride in its pharmaceutical dosage forms is developed employing Kromasil C18 column, mobile phase consisted of sodium acetate buffer-acetonitrile (65:35) with UV-detection at 226 nm. The method was validated as per ICH guidelines for specificity, linearity, precision and accuracy. Forced degradation studies were performed on the bulk sample using 0.5 N HCl, 0.1 N NaOH, 33 % H2O2 and heat (50°C).
AB - A stability indicating HPLC method for the analysis of venlafaxine hydrochloride in its pharmaceutical dosage forms is developed employing Kromasil C18 column, mobile phase consisted of sodium acetate buffer-acetonitrile (65:35) with UV-detection at 226 nm. The method was validated as per ICH guidelines for specificity, linearity, precision and accuracy. Forced degradation studies were performed on the bulk sample using 0.5 N HCl, 0.1 N NaOH, 33 % H2O2 and heat (50°C).
M3 - Article
SN - 0970-7077
VL - 20
SP - 6297
EP - 6300
JO - Asian Journal of Chemistry
JF - Asian Journal of Chemistry
IS - 8
ER -