TY - JOUR
T1 - Structurally nanoengineered antimicrobial peptide polymers
T2 - design, synthesis and biomedical applications
AU - Ramamurthy, Ronisha
AU - Mehta, Chetan H.
AU - Nayak, Usha Y.
N1 - Funding Information:
The authors would like to express their sincere gratitude to Manipal Academy of Higher Education, Manipal, for providing facilities for the literature search and other facilities. Authors are also thankful to the Indian Council of Medical Research (ICMR), New Delhi, Ref. No 35/13/020-Nano/BMS for the fund support.
Funding Information:
The authors would like to express their sincere gratitude to Manipal Academy of Higher Education, Manipal, for providing facilities for the literature search and other?facilities. Authors are also thankful to the Indian Council of Medical Research (ICMR), New Delhi, Ref. No 35/13/020-Nano/BMS for the fund support.
Funding Information:
Open access funding provided by Manipal Academy of Higher Education, Manipal. Fund support by Indian Council of Medical Research (ICMR), New Delhi, Ref. No 35/13/020-Nano/BMS to work in this area.
Publisher Copyright:
© 2021, The Author(s).
PY - 2021/8
Y1 - 2021/8
N2 - Abstract: Antimicrobial resistance not only increases the contagiousness of infectious diseases but also a threat for the future as it is one of the health care concern around the globe. Conventional antibiotics are unsuccessful in combating chronic infections caused by multidrug-resistant (MDR) bacteria, therefore it is important to design and develop novel strategies to tackle this problems. Among various novel strategies, Structurally Nanoengineered Antimicrobial Peptide Polymers (SNAPPs) have been introduced in recent years to overcome this global health care issue and they are found to be more efficient in their performance. Many facile methods are adapted to synthesize complex SNAPPs with required dimensions and unique functionalities. Their unique characteristics and remarkable properties have been exploited for their immense applications in various fields including biomedicine, targeting therapies, gene delivery, bioimaging, and many more. This review article deals with its background, design, synthesis, mechanism of action, and wider applications in various fields of SNAPPs. Graphic abstract: [Figure not available: see fulltext.].
AB - Abstract: Antimicrobial resistance not only increases the contagiousness of infectious diseases but also a threat for the future as it is one of the health care concern around the globe. Conventional antibiotics are unsuccessful in combating chronic infections caused by multidrug-resistant (MDR) bacteria, therefore it is important to design and develop novel strategies to tackle this problems. Among various novel strategies, Structurally Nanoengineered Antimicrobial Peptide Polymers (SNAPPs) have been introduced in recent years to overcome this global health care issue and they are found to be more efficient in their performance. Many facile methods are adapted to synthesize complex SNAPPs with required dimensions and unique functionalities. Their unique characteristics and remarkable properties have been exploited for their immense applications in various fields including biomedicine, targeting therapies, gene delivery, bioimaging, and many more. This review article deals with its background, design, synthesis, mechanism of action, and wider applications in various fields of SNAPPs. Graphic abstract: [Figure not available: see fulltext.].
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U2 - 10.1007/s11274-021-03109-z
DO - 10.1007/s11274-021-03109-z
M3 - Review article
AN - SCOPUS:85110470529
SN - 0959-3993
VL - 37
JO - World Journal of Microbiology and Biotechnology
JF - World Journal of Microbiology and Biotechnology
IS - 8
M1 - 139
ER -
