Studies on γ-glutamyl transpeptidase of human urine

K. Rambabu, T.N. Pattabiraman

Research output: Contribution to journalArticlepeer-review


A simple and rapid method suitable for clinical laboratories, for the removal of the inhibitors in urine of γ-glutamyl transpeptidase activity, using an ion-retardation resin, is described. Gel chromatography of urine resulted in appreciable loss of the enzyme activity. Freezing at -5°C and thawing, did not affect the activity of the enzyme. Dimethyl sulfoxide and polyvinyl pyrrolidone up to a concentration of 20% did not have any effect on the transpeptidase activity. Urea, creatinine and NaCl at levels found in normal urine did not inhibit the transpeptidase. © 1976.
Original languageEnglish
Pages (from-to)251-255
Number of pages5
JournalClinica Chimica Acta
Issue number2
Publication statusPublished - 1976
Externally publishedYes


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