Studies on some N-bridged heterocycles derived from bis- [4-amino-5-mercapto-1,2,4-triazol-3-yl] alkanes

B. Shivarama Holla; Richard Gonsalves; Shalini Shenoy

doi:10.1016/S0014-827X(98)00068-8

Studies on some N-bridged heterocycles derived from bis- [4-amino-5-mercapto-1,2,4-triazol-3-yl] alkanes

B. Shivarama Holla^*
, Richard Gonsalves
, Shalini Shenoy

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

130 Citations (Scopus)

Abstract

A series of bis-[4-amino-5-mercapto-1,2,4-triazol-3-yl] alkanes have been synthesized and were converted into bis-[1,2,4-triazolo[3,4-b]-1,3,4-thiadiazol-4-yl] alkanes. The newly synthesized compounds were characterized by analytical IR, NMR and mass spectral studies. Some of the newly synthesized compounds were screened for their antibacterial properties and exhibited activity with MIC in the range 3-12.5 μg/ml.

Original language	English
Pages (from-to)	574-578
Number of pages	5
Journal	Farmaco
Volume	53
Issue number	8-9
DOIs	https://doi.org/10.1016/S0014-827X(98)00068-8
Publication status	Published - 30-08-1998

All Science Journal Classification (ASJC) codes

Pharmaceutical Science
Drug Discovery

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10.1016/S0014-827X(98)00068-8

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AU - Holla, B. Shivarama

AU - Gonsalves, Richard

AU - Shenoy, Shalini

PY - 1998/8/30

Y1 - 1998/8/30

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AB - A series of bis-[4-amino-5-mercapto-1,2,4-triazol-3-yl] alkanes have been synthesized and were converted into bis-[1,2,4-triazolo[3,4-b]-1,3,4-thiadiazol-4-yl] alkanes. The newly synthesized compounds were characterized by analytical IR, NMR and mass spectral studies. Some of the newly synthesized compounds were screened for their antibacterial properties and exhibited activity with MIC in the range 3-12.5 μg/ml.

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ER -

Studies on some N-bridged heterocycles derived from bis- [4-amino-5-mercapto-1,2,4-triazol-3-yl] alkanes

Abstract

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