TY - JOUR
T1 - Study of association of preoperative glycosylated haemoglobin level and outcome after cardiac surgery
AU - Joshi, Harshil
AU - Kumara, Vijaya
AU - Rai, Guruprasad
AU - Bishnoi, Aravind Kumar
N1 - Publisher Copyright:
© 2020, College of Anaesthesiologists of Sri Lanka. All rights reserved.
Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2020
Y1 - 2020
N2 - Background: Diabetes mellitus involves 8.7% of the adult community in India, and its preponderance is rising. Diabetes is an independent risk factor for complications after open cardiac surgery. Poor glycaemic control, measured by glycosylated haemoglobin A1C (HbA1c), is associated with high incidence of micro and macroangiopathy. HbA1c reflects the patient's prevailing sugar control over the previous 120-150 days. Perioperative cardiac surgical risk scoring systems like Euro Score and STS scoring systems do not include HbA1c level as risk factor. We intended to study the correlation of preoperative HbA1c level and outcome after cardiac surgery. Methodology: A total of 350 patients who had undergone elective cardiac surgery were included. All patients were stratified into two groups, Group 1 with HbA1c level < 7%, Group 2 >7%. Intraoperative and postoperative adverse events were documented retrospectively. The two groups of patients were compared with regard to their demographic data, operation risk, mortality and morbidity. Results: Overall incidence of major adverse events (7.7%) and mortality (4.8%) were very low. Incidence of sternal wound infection and prolonged ventilator support (> 24hrs) were significant in group 2 compared to group 1(p values were 0.03 and 0.01 respectively). Conclusion: Preoperative HbA1c level may provide more accurate prognostic information about outcomes after all major open cardiac surgeries compared with a diabetes status alone.
AB - Background: Diabetes mellitus involves 8.7% of the adult community in India, and its preponderance is rising. Diabetes is an independent risk factor for complications after open cardiac surgery. Poor glycaemic control, measured by glycosylated haemoglobin A1C (HbA1c), is associated with high incidence of micro and macroangiopathy. HbA1c reflects the patient's prevailing sugar control over the previous 120-150 days. Perioperative cardiac surgical risk scoring systems like Euro Score and STS scoring systems do not include HbA1c level as risk factor. We intended to study the correlation of preoperative HbA1c level and outcome after cardiac surgery. Methodology: A total of 350 patients who had undergone elective cardiac surgery were included. All patients were stratified into two groups, Group 1 with HbA1c level < 7%, Group 2 >7%. Intraoperative and postoperative adverse events were documented retrospectively. The two groups of patients were compared with regard to their demographic data, operation risk, mortality and morbidity. Results: Overall incidence of major adverse events (7.7%) and mortality (4.8%) were very low. Incidence of sternal wound infection and prolonged ventilator support (> 24hrs) were significant in group 2 compared to group 1(p values were 0.03 and 0.01 respectively). Conclusion: Preoperative HbA1c level may provide more accurate prognostic information about outcomes after all major open cardiac surgeries compared with a diabetes status alone.
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U2 - 10.4038/slja.v28i1.8467
DO - 10.4038/slja.v28i1.8467
M3 - Article
AN - SCOPUS:85079458241
SN - 1391-8834
VL - 28
SP - 14
EP - 18
JO - Sri Lankan Journal of Anaesthesiology
JF - Sri Lankan Journal of Anaesthesiology
IS - 1
ER -