Suicidal zinc phosphide poisoning unmasking brugada syndrome and triggering near fatal ventricular arrhythmia

Mukund A. Prabhu; Reynold Agustinus; Jayaprakash Shenthar

doi:10.1111/pace.12749

Suicidal zinc phosphide poisoning unmasking brugada syndrome and triggering near fatal ventricular arrhythmia

Mukund A. Prabhu^*
, Reynold Agustinus
, Jayaprakash Shenthar

^*Corresponding author for this work

Department of Cardiology, Kasturba Medical College, Manipal

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

Abstract

Brugada syndrome (BrS) is an inherited channelopathy associated with increased incidence of ventricular arrhythmias and has many acquired triggers. Zinc phosphide (ZnP) is a rodenticide and is commonly implicated in suicidal poison ingestion. ZnP poisoning can cause myocardial toxicity and death. We report a case of ZnP poisoning that triggered a type I Brugada pattern and ventricular fibrillation in a 67-year-old male. He had no other features of toxicity and recovered later. As metal phosphide is the commonest toxin involved in suicidal poisoning in India and BrS being endemic here, this case highlights an important clinical problem.

Original language	English
Pages (from-to)	198-201
Number of pages	4
Journal	PACE - Pacing and Clinical Electrophysiology
Volume	39
Issue number	2
DOIs	https://doi.org/10.1111/pace.12749
Publication status	Published - 01-02-2016

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This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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Cardiology and Cardiovascular Medicine

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10.1111/pace.12749

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abstract = "Brugada syndrome (BrS) is an inherited channelopathy associated with increased incidence of ventricular arrhythmias and has many acquired triggers. Zinc phosphide (ZnP) is a rodenticide and is commonly implicated in suicidal poison ingestion. ZnP poisoning can cause myocardial toxicity and death. We report a case of ZnP poisoning that triggered a type I Brugada pattern and ventricular fibrillation in a 67-year-old male. He had no other features of toxicity and recovered later. As metal phosphide is the commonest toxin involved in suicidal poisoning in India and BrS being endemic here, this case highlights an important clinical problem.",

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AU - Prabhu, Mukund A.

AU - Agustinus, Reynold

AU - Shenthar, Jayaprakash

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N2 - Brugada syndrome (BrS) is an inherited channelopathy associated with increased incidence of ventricular arrhythmias and has many acquired triggers. Zinc phosphide (ZnP) is a rodenticide and is commonly implicated in suicidal poison ingestion. ZnP poisoning can cause myocardial toxicity and death. We report a case of ZnP poisoning that triggered a type I Brugada pattern and ventricular fibrillation in a 67-year-old male. He had no other features of toxicity and recovered later. As metal phosphide is the commonest toxin involved in suicidal poisoning in India and BrS being endemic here, this case highlights an important clinical problem.

AB - Brugada syndrome (BrS) is an inherited channelopathy associated with increased incidence of ventricular arrhythmias and has many acquired triggers. Zinc phosphide (ZnP) is a rodenticide and is commonly implicated in suicidal poison ingestion. ZnP poisoning can cause myocardial toxicity and death. We report a case of ZnP poisoning that triggered a type I Brugada pattern and ventricular fibrillation in a 67-year-old male. He had no other features of toxicity and recovered later. As metal phosphide is the commonest toxin involved in suicidal poisoning in India and BrS being endemic here, this case highlights an important clinical problem.

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Suicidal zinc phosphide poisoning unmasking brugada syndrome and triggering near fatal ventricular arrhythmia

Abstract

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