Synthesis and anti-inflammatory activity of substituted (E)-4-phenyl-3-buten-2-ones

G. Elias, M.N.A. Rao

Research output: Contribution to journalArticlepeer-review

48 Citations (Scopus)


A series of ring substituted 4-phenyl-3-buten-2-ones was synthesized and evaluated for anti-inflammatory activity by carrageenan-induced paw edema in rats. Several compounds showed significant activity, among them, the 4-acetyloxy-3-methoxy derivative was the most active and the 4-methoxy derivatives were the least effective. © 1988.
Original languageUndefined/Unknown
Pages (from-to)379-380
Number of pages2
JournalEuropean Journal of Medicinal Chemistry
Issue number4
Publication statusPublished - 1988
Externally publishedYes

Cite this