Synthesis and biological activity of some 2-(6-methoxynaphthyl) propionamido azetidine-2-ones

R.H. Udupi, N. Kasinath, A.R. Bhat

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The hydrazide of 2-(6-methoxy α-naphthyl)-propionic acid (Naproxen) was converted to the Schiff's bases which in turn on reacting with aryl and aryloxy acetyl chlorides yielded the corresponding azetidin-2-ones (4-a-c and 5 a-t). Representative compounds screened for antitubercular activity were proved to be equipotent with streptomycin.
Original languageUndefined/Unknown
Pages (from-to)221-224
Number of pages4
JournalIndian Journal of Heterocyclic Chemistry
Issue number3
Publication statusPublished - 1998

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