Synthesis and biological activity of some 2-(6-methoxynaphthyl) propionamido azetidine-2-ones

R.H. Udupi; N. Kasinath; A.R. Bhat

Synthesis and biological activity of some 2-(6-methoxynaphthyl) propionamido azetidine-2-ones

R.H. Udupi
, N. Kasinath
, A.R. Bhat

Manipal College of Pharmaceutical Sciences, Manipal

Research output: Contribution to journal › Article › peer-review

19 Citations (Scopus)

Abstract

The hydrazide of 2-(6-methoxy α-naphthyl)-propionic acid (Naproxen) was converted to the Schiff's bases which in turn on reacting with aryl and aryloxy acetyl chlorides yielded the corresponding azetidin-2-ones (4-a-c and 5 a-t). Representative compounds screened for antitubercular activity were proved to be equipotent with streptomycin.

Original language	Undefined/Unknown
Pages (from-to)	221-224
Number of pages	4
Journal	Indian Journal of Heterocyclic Chemistry
Volume	7
Issue number	3
Publication status	Published - 1998

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Cite this

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title = "Synthesis and biological activity of some 2-(6-methoxynaphthyl) propionamido azetidine-2-ones",

abstract = "The hydrazide of 2-(6-methoxy α-naphthyl)-propionic acid (Naproxen) was converted to the Schiff's bases which in turn on reacting with aryl and aryloxy acetyl chlorides yielded the corresponding azetidin-2-ones (4-a-c and 5 a-t). Representative compounds screened for antitubercular activity were proved to be equipotent with streptomycin.",

author = "R.H. Udupi and N. Kasinath and A.R. Bhat",

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year = "1998",

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pages = "221--224",

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TY - JOUR

T1 - Synthesis and biological activity of some 2-(6-methoxynaphthyl) propionamido azetidine-2-ones

AU - Udupi, R.H.

AU - Kasinath, N.

AU - Bhat, A.R.

N1 - cited By 16

PY - 1998

Y1 - 1998

N2 - The hydrazide of 2-(6-methoxy α-naphthyl)-propionic acid (Naproxen) was converted to the Schiff's bases which in turn on reacting with aryl and aryloxy acetyl chlorides yielded the corresponding azetidin-2-ones (4-a-c and 5 a-t). Representative compounds screened for antitubercular activity were proved to be equipotent with streptomycin.

AB - The hydrazide of 2-(6-methoxy α-naphthyl)-propionic acid (Naproxen) was converted to the Schiff's bases which in turn on reacting with aryl and aryloxy acetyl chlorides yielded the corresponding azetidin-2-ones (4-a-c and 5 a-t). Representative compounds screened for antitubercular activity were proved to be equipotent with streptomycin.

M3 - Article

SN - 0971-1627

VL - 7

SP - 221

EP - 224

JO - Indian Journal of Heterocyclic Chemistry

JF - Indian Journal of Heterocyclic Chemistry

IS - 3

ER -