@article{6a9be8bbcb4b48dc962487e3a4b87e20,
title = "Synthesis and biological evaluation of new benzofuranyl isoxazoles as antitubercular, antibacterial and antifungal agents",
abstract = "Substituted benzofuran chalcones (2a-n) were prepared by the reaction of 2-acetyl benzofuran (1) with different aromatic aldehydes in presence of strong base. Benzofuran chalcones (2a-n) on cyclocondensation with hydroxylamine hydrochloride in presence of sodium acetate, gave various 3-(1-benzofuran-2-yl)- 5-phenylisoxazoles (3a-n). The structure of benzofuran isoxazoles 3a-n have been established on the basis of spectral (IR, 1H NMR, Mass) data. The benzofuran isoxazoles were evaluated for their, antitubercular, antimicrobial and antiinflammatory activities. Some of the compounds have shown promising antitubercular and antibacterial activity.",
author = "K. Manna and Y.K. Agarwal and K.K. Srinivasan",
note = "Cited By :4 Export Date: 10 November 2017 Correspondence Address: Manna, K.; Institute of Pharmacy, Nirma University of Science and Technology, Ahmedabad, India References: Zboinska, E., Sztajer, H., Lejezak, B., Kafarski, P., (1990) FEMS Microbiol. Lett, 70, p. 23; Sangapure, S.S., Veeresh, D.H., Yadav, B., (2000) Indian J. Heterocyclic Chem, 10, p. 21; Sangapure, S.S., Veeresh, D.H., Yadav, B., (2000) Indian J. Heterocyclic Chem, 10, p. 21; Rescifina, A., Chiacchio, M.A., Corsaro, A., De Clercq, E., lannazzo, D., Mastino, A., Piperno, A., Valveri, V., (2006) J. Med. Chem, 49, p. 709; Kaffy, J., Pontikis, R., Carrez, D., Croisy, A., Monneret, C., Florent, J.C., (2006) Bioorg Med. Chem, 27, p. 22",
year = "2008",
language = "English",
volume = "18",
pages = "87--88",
journal = "Indian Journal of Heterocyclic Chemistry",
issn = "0971-1627",
publisher = "National Academy of Chemistry",
number = "1",
}