Abstract
Some of the Schiff bases of aminothiazolylbromocoumarin are synthesized by the reaction between 2′-amino-4′-(6-bromo-3-coumarinyl) thiazole and substituted aromatic aldehydes. The former is obtained by cyclization of 3-bromoacetyl-6-bromocoumarin and thiourea. The resulting compounds are characterized by spectral data and evaluated for analgesic and anti-inflammatory activity by acetic acid-induced abdominal constriction method and carrageenan induced rat hind paw oedema method respectively. Some of the compounds have shown interesting biological activity based on the presence of certain functional groups.
| Original language | English |
|---|---|
| Pages (from-to) | 407-411 |
| Number of pages | 5 |
| Journal | Asian Journal of Chemistry |
| Volume | 16 |
| Issue number | 1 |
| Publication status | Published - 01-01-2004 |
All Science Journal Classification (ASJC) codes
- Chemistry(all)