Synthesis based on cyclohexadienes. Part 9. Total synthesis of (±)-seychellene

G. S.R. Subba Rao; K. Vijaya Bhaskar

Synthesis based on cyclohexadienes. Part 9. Total synthesis of (±)-seychellene

G. S.R. Subba Rao^*, K. Vijaya Bhaskar

^*Corresponding author for this work

Department of Pharmaceutical Chemistry, Manipal College of Pharmaceutical Sciences, Manipal

Research output: Contribution to journal › Article › peer-review

6 Citations (Scopus)

Abstract

A new strategy for the total synthesis of (±)-seychellene 1 is described. The key step is an intramolecular Michael addition involving a 6-exo cyclisation with a vinyl radical derived from the acetylenic compound 11, obtained from the bicyclo[2.2.2]octene adduct 5 to the tricyclic intermediates 14 and 15.

Original language	English
Pages (from-to)	2813-2816
Number of pages	4
Journal	Journal of the Chemical Society, Perkin Transactions 1
Issue number	22
Publication status	Published - 1993

All Science Journal Classification (ASJC) codes

General Chemistry

Cite this

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title = "Synthesis based on cyclohexadienes. Part 9. Total synthesis of (±)-seychellene",

abstract = "A new strategy for the total synthesis of (±)-seychellene 1 is described. The key step is an intramolecular Michael addition involving a 6-exo cyclisation with a vinyl radical derived from the acetylenic compound 11, obtained from the bicyclo[2.2.2]octene adduct 5 to the tricyclic intermediates 14 and 15.",

author = "\{Subba Rao\}, \{G. S.R.\} and \{Vijaya Bhaskar\}, K.",

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journal = "Journal of the Chemical Society, Perkin Transactions 1",

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T1 - Synthesis based on cyclohexadienes. Part 9. Total synthesis of (±)-seychellene

AU - Subba Rao, G. S.R.

AU - Vijaya Bhaskar, K.

PY - 1993

Y1 - 1993

N2 - A new strategy for the total synthesis of (±)-seychellene 1 is described. The key step is an intramolecular Michael addition involving a 6-exo cyclisation with a vinyl radical derived from the acetylenic compound 11, obtained from the bicyclo[2.2.2]octene adduct 5 to the tricyclic intermediates 14 and 15.

AB - A new strategy for the total synthesis of (±)-seychellene 1 is described. The key step is an intramolecular Michael addition involving a 6-exo cyclisation with a vinyl radical derived from the acetylenic compound 11, obtained from the bicyclo[2.2.2]octene adduct 5 to the tricyclic intermediates 14 and 15.

UR - https://www.scopus.com/pages/publications/37049073129

UR - https://www.scopus.com/inward/citedby.url?scp=37049073129&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:37049073129

SN - 1472-7781

SP - 2813

EP - 2816

JO - Journal of the Chemical Society, Perkin Transactions 1

JF - Journal of the Chemical Society, Perkin Transactions 1

IS - 22

ER -

Synthesis based on cyclohexadienes. Part 9. Total synthesis of (±)-seychellene

Abstract

All Science Journal Classification (ASJC) codes

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