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Synthesis, characterization and antibacterial activity studies on some fluorine containing quinoline-4-carboxylic acids and their derivatives

  • B. Shivarama Holla*
  • , K. Narayana Poojary
  • , Boja Poojary
  • , K. Subrahmanya Bhat
  • , N. Suchetha Kumari
  • *Corresponding author for this work

    Research output: Contribution to journalArticlepeer-review

    Abstract

    A series of 3-substituted-1,2,4-triazolo[3,4-6]-1,3,4-thiadiazol-6-yl-2-(2, 4-dichloro-5-fluorophenyl)quinolines 5 have been synthesized by the condensation of hitherto unreported quinoline-4-carboxylic acids 3 with various 3-substituted-4-amino-5-mercapto-1,2,4-triazoles 4. The structures of newly synthesized compounds have been confirmed on the basis of elemental analysis, IR, 1H NMR and mass spectral data. The newly synthesized compounds are evaluated for their antibacterial activities.

    Original languageEnglish
    Pages (from-to)2114-2119
    Number of pages6
    JournalIndian Journal of Chemistry - Section B Organic and Medicinal Chemistry
    Volume44
    Issue number10
    Publication statusPublished - 10-2005

    All Science Journal Classification (ASJC) codes

    • Pharmacology, Toxicology and Pharmaceutics(all)
    • Organic Chemistry

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