TY - JOUR
T1 - Synthesis, characterization and single crystal studies of 3-cyclopropyl-3, 4-dihydroquinazolin-2(1H)-one
AU - Shetty, Nitinkumar S.
AU - Nadaf, Y. F.
AU - Bilehal, Dinesh
AU - Shyamkumar, V.
AU - Gaonkar, Santosh L.
PY - 2016
Y1 - 2016
N2 - The paper describes industrially scalable synthesis and single crystal studies of 3-cyclopropyl-3,4-dihydroquinazolin-2(1H)-one 4, a versatile intermediate in the synthesis of number of biologically active compounds. The target compound has been characterized by LC-MS, 1H NMR and IR. The crystal structure analysis shows that the title compound crystallizes in monoclinic class under the space group P 1 21/n 1 with cell parameters, a = 10.273(2) Å, b = 8.3227(19) Å, c = 11.623(3) Å, β = 104.980(3)°, V = 960.0(4) Å3 and Z=4.
AB - The paper describes industrially scalable synthesis and single crystal studies of 3-cyclopropyl-3,4-dihydroquinazolin-2(1H)-one 4, a versatile intermediate in the synthesis of number of biologically active compounds. The target compound has been characterized by LC-MS, 1H NMR and IR. The crystal structure analysis shows that the title compound crystallizes in monoclinic class under the space group P 1 21/n 1 with cell parameters, a = 10.273(2) Å, b = 8.3227(19) Å, c = 11.623(3) Å, β = 104.980(3)°, V = 960.0(4) Å3 and Z=4.
UR - http://www.scopus.com/inward/record.url?scp=84995450954&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84995450954&partnerID=8YFLogxK
U2 - 10.13005/ojc/320544
DO - 10.13005/ojc/320544
M3 - Article
AN - SCOPUS:84995450954
SN - 0970-020X
VL - 32
SP - 2707
EP - 2712
JO - Oriental Journal of Chemistry
JF - Oriental Journal of Chemistry
IS - 5
ER -