Synthesis of 3-methylflavones and their antioxidant and antibacterial activities

B. S. Jayashree, Afroze Alam, Yogendra Nayak, D. Vijay Kumar

Research output: Contribution to journalArticlepeer-review

14 Citations (Scopus)


An attempt was made to synthesise newer 3-methylflavones with various substitution on the ring A and B of 2-phenylchromen-4-one. They were evaluated for antioxidant activity and antibacterial activity against the Gram-positive and Gram-negative bacteria. Five test compounds exhibited DPPH radical scavenging activity with IC50 below 100 lg/ml, and the same test compounds exhibited 50-100% growth inhibition in Gram-positive bacteria against standard Amoxicillin.

Original languageEnglish
Pages (from-to)1991-1996
Number of pages6
JournalMedicinal Chemistry Research
Issue number8
Publication statusPublished - 08-2012

All Science Journal Classification (ASJC) codes

  • Pharmacology, Toxicology and Pharmaceutics(all)
  • Organic Chemistry


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