Synthesis of some new biologically active thiadiazolotriazinones - Part II

B. Shivarama Holla; B. K. Sarojini; K. Shridhara; Georgy Antony

doi:10.1016/S0014-827X(99)00008-7

Synthesis of some new biologically active thiadiazolotriazinones - Part II

B. Shivarama Holla^*
, B. K. Sarojini
, K. Shridhara
, Georgy Antony

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

25 Citations (Scopus)

Abstract

4-Amino-6-phenyl/methyl-3-mercapto-1,2,4-triazin-5(4H)-ones (1) are condensed with an aromatic carboxylic acid, aryloxyacetic acid or anilinoacetic acid (2), to yield 7-substituted-3-phenyl/methyl-4H-1,3,4-thiadiazolo-[2,3-c]-1,2,4-triazin-4-ones (3). Phosphorus oxychloride is used as a cyclizing agent. All the synthesized compounds are screened for their antibacterial activities against S. aureus, E. coli, P. aeruginosa and G. bacillus.

Original language	English
Pages (from-to)	149-151
Number of pages	3
Journal	Farmaco
Volume	54
Issue number	3
DOIs	https://doi.org/10.1016/S0014-827X(99)00008-7
Publication status	Published - 31-03-1999
Externally published	Yes

All Science Journal Classification (ASJC) codes

Drug Discovery
Pharmaceutical Science

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10.1016/S0014-827X(99)00008-7

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title = "Synthesis of some new biologically active thiadiazolotriazinones - Part II",

abstract = "4-Amino-6-phenyl/methyl-3-mercapto-1,2,4-triazin-5(4H)-ones (1) are condensed with an aromatic carboxylic acid, aryloxyacetic acid or anilinoacetic acid (2), to yield 7-substituted-3-phenyl/methyl-4H-1,3,4-thiadiazolo-[2,3-c]-1,2,4-triazin-4-ones (3). Phosphorus oxychloride is used as a cyclizing agent. All the synthesized compounds are screened for their antibacterial activities against S. aureus, E. coli, P. aeruginosa and G. bacillus.",

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year = "1999",

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doi = "10.1016/S0014-827X(99)00008-7",

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T1 - Synthesis of some new biologically active thiadiazolotriazinones - Part II

AU - Holla, B. Shivarama

AU - Sarojini, B. K.

AU - Shridhara, K.

AU - Antony, Georgy

PY - 1999/3/31

Y1 - 1999/3/31

N2 - 4-Amino-6-phenyl/methyl-3-mercapto-1,2,4-triazin-5(4H)-ones (1) are condensed with an aromatic carboxylic acid, aryloxyacetic acid or anilinoacetic acid (2), to yield 7-substituted-3-phenyl/methyl-4H-1,3,4-thiadiazolo-[2,3-c]-1,2,4-triazin-4-ones (3). Phosphorus oxychloride is used as a cyclizing agent. All the synthesized compounds are screened for their antibacterial activities against S. aureus, E. coli, P. aeruginosa and G. bacillus.

AB - 4-Amino-6-phenyl/methyl-3-mercapto-1,2,4-triazin-5(4H)-ones (1) are condensed with an aromatic carboxylic acid, aryloxyacetic acid or anilinoacetic acid (2), to yield 7-substituted-3-phenyl/methyl-4H-1,3,4-thiadiazolo-[2,3-c]-1,2,4-triazin-4-ones (3). Phosphorus oxychloride is used as a cyclizing agent. All the synthesized compounds are screened for their antibacterial activities against S. aureus, E. coli, P. aeruginosa and G. bacillus.

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M3 - Article

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SN - 0014-827X

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ER -

Synthesis of some new biologically active thiadiazolotriazinones - Part II

Abstract

All Science Journal Classification (ASJC) codes

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