Temozolomide and its stability—a critical factor

Zenab Attari; C. Mallikarjuna Rao; Lalit Kumar; K. B. Koteshwara

doi:10.1166/asl.2017.8486

Temozolomide and its stability—a critical factor

Zenab Attari
, C. Mallikarjuna Rao
, Lalit Kumar
, K. B. Koteshwara^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

6 Citations (Scopus)

Abstract

Temozolomide is an alkylating agent, used in the treatment of glioblastoma multiforme. The characterization of the pure drug and its expired batch was carried out to evaluate the changes occurred due to degradation of the drug. FT-IR spectrocscopy, DSC analysis and drug content estimation were carried out. The observations indicated the changes in the drug peak and content after expiry period.

Original language	English
Pages (from-to)	1841-1845
Number of pages	5
Journal	Advanced Science Letters
Volume	23
Issue number	3
DOIs	https://doi.org/10.1166/asl.2017.8486
Publication status	Published - 01-03-2017

All Science Journal Classification (ASJC) codes

Health(social science)
General Computer Science
Education
General Mathematics
General Environmental Science
General Engineering
General Energy

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10.1166/asl.2017.8486

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abstract = "Temozolomide is an alkylating agent, used in the treatment of glioblastoma multiforme. The characterization of the pure drug and its expired batch was carried out to evaluate the changes occurred due to degradation of the drug. FT-IR spectrocscopy, DSC analysis and drug content estimation were carried out. The observations indicated the changes in the drug peak and content after expiry period.",

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AU - Kumar, Lalit

AU - Koteshwara, K. B.

PY - 2017/3/1

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N2 - Temozolomide is an alkylating agent, used in the treatment of glioblastoma multiforme. The characterization of the pure drug and its expired batch was carried out to evaluate the changes occurred due to degradation of the drug. FT-IR spectrocscopy, DSC analysis and drug content estimation were carried out. The observations indicated the changes in the drug peak and content after expiry period.

AB - Temozolomide is an alkylating agent, used in the treatment of glioblastoma multiforme. The characterization of the pure drug and its expired batch was carried out to evaluate the changes occurred due to degradation of the drug. FT-IR spectrocscopy, DSC analysis and drug content estimation were carried out. The observations indicated the changes in the drug peak and content after expiry period.

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M3 - Article

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JO - Advanced Science Letters

JF - Advanced Science Letters

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Temozolomide and its stability—a critical factor

Abstract

All Science Journal Classification (ASJC) codes

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