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Tenofovir disoproxil fumarate-induced distal renal tubular acidosis: A case report

Research output: Contribution to journalArticlepeer-review

Abstract

Tenofovir disoproxil fumarate (TDF) is an anti-retroviral drug that is known to cause nephrotoxicity including renal tubular acidosis (RTA). With increasing literature on proximal RTA caused by TDF, reports on distal RTA are scarce, with only one case reported so far. We report a case of distal RTA in patient living with human immunodeficiency virus, who presented with nausea and fatigue giving a history of TDF-based therapy for two years. Laboratory investigations revealed non-anion gap metabolic acidosis, positive urine anion gap, hyperchloremia, and hypokalemia. The patient improved after discontinuing TDF and supportive management.

Original languageEnglish
Pages (from-to)276-279
Number of pages4
JournalInternational Journal of STD and AIDS
Volume31
Issue number3
DOIs
Publication statusPublished - 01-03-2020

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

All Science Journal Classification (ASJC) codes

  • Dermatology
  • Public Health, Environmental and Occupational Health
  • Pharmacology (medical)
  • Infectious Diseases

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