The APACHE II score and mortality in relation to hypocalcaemia in critically ill patients

Ravindra Prabhu Attur, Waqas Wahid Baig, Prakash Kori, S. Vishwanath, Madhur Agrawal, Sonal Sukreet, Mungli Prakash

Research output: Contribution to journalArticlepeer-review


Background: Electrolyte imbalance is commonly seen in the intensive care unit (ICU) patients. Hypocalcaemia is one of the most common electrolyte deficiencies found in these patients. Methods: This study was conducted on 110 critically ill patients who were admitted to the ICU (71 males and 39 females). The patients were classified into two groups, group I (patients expired) and group II (patients completely recovered). We further subclassified the patients, based on the APACHE II score into three groups as group A (APACHE II score <15), group B (APACHE II score 15-25) and group C (APACHE II score >25). The serum calcium, magnesium and albumin levels were determined by using a clinical chemistry auto analyzer. Corrected calcium was calculated by using formula. Type of study: Prospective/Retrospective Results: There was a significant decrease in the calcium and the corrected calcium levels in the group I patients as compared to those in group II (p<0.05). There was significant hypocalcaemia in the group C patients as compared to the group A and group B patients (p<0.01). The calcium levels correlated negatively with the APACHE II score. Conclusions: There is a direct correlation between hypocalcaemia and mortality in the critically ill patients. Hypocalcaemia and the APACHE II score were negatively correlated.

Original languageEnglish
Pages (from-to)708-710
Number of pages3
JournalJournal of Clinical and Diagnostic Research
Issue number4
Publication statusPublished - 22-08-2011

All Science Journal Classification (ASJC) codes

  • Clinical Biochemistry


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