The integration of genome-based information for common diseases into health policy and healthcare as a major challenge for Public Health Genomics: The example of the methylenetetrahydrofolate reductase gene in non-cancer diseases

Stefania Boccia; Angela Brand; Helmut Brand; Gualtiero Ricciardi

doi:10.1016/j.mrfmmm.2008.10.003

The integration of genome-based information for common diseases into health policy and healthcare as a major challenge for Public Health Genomics: The example of the methylenetetrahydrofolate reductase gene in non-cancer diseases

Stefania Boccia, Angela Brand, Helmut Brand, Gualtiero Ricciardi

Research output: Contribution to journal › Article › peer-review

10 Citations (SciVal)

Abstract

Whereas medicine is currently undergoing remarkable developments from its morphological and phenotype orientation to a molecular and genotype orientation, promoting the importance of prognosis and prediction, the discussion about the role of genome-based information for epidemiological research and public health still is at the beginning. Public Health Genomics (PHG) contributes to this discussion by focussing on the use of genome-based information for epidemiological research, surveillance systems, health policy development, individual health information management and effective health services. The article focuses on the role of the methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms in non-cancer diseases to demonstrate the urgent need for a responsible and systematic translation of genome-based information into health policy and healthcare.

Original language	English
Pages (from-to)	27-34
Number of pages	8
Journal	Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis
Volume	667
Issue number	1-2
DOIs	https://doi.org/10.1016/j.mrfmmm.2008.10.003
Publication status	Published - 10-07-2009

All Science Journal Classification (ASJC) codes

Molecular Biology
Genetics
Health, Toxicology and Mutagenesis

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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Boccia, S., Brand, A., Brand, H., & Ricciardi, G. (2009). The integration of genome-based information for common diseases into health policy and healthcare as a major challenge for Public Health Genomics: The example of the methylenetetrahydrofolate reductase gene in non-cancer diseases. Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 667(1-2), 27-34. https://doi.org/10.1016/j.mrfmmm.2008.10.003

Boccia, Stefania ; Brand, Angela ; Brand, Helmut et al. / The integration of genome-based information for common diseases into health policy and healthcare as a major challenge for Public Health Genomics : The example of the methylenetetrahydrofolate reductase gene in non-cancer diseases. In: Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 2009 ; Vol. 667, No. 1-2. pp. 27-34.

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abstract = "Whereas medicine is currently undergoing remarkable developments from its morphological and phenotype orientation to a molecular and genotype orientation, promoting the importance of prognosis and prediction, the discussion about the role of genome-based information for epidemiological research and public health still is at the beginning. Public Health Genomics (PHG) contributes to this discussion by focussing on the use of genome-based information for epidemiological research, surveillance systems, health policy development, individual health information management and effective health services. The article focuses on the role of the methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms in non-cancer diseases to demonstrate the urgent need for a responsible and systematic translation of genome-based information into health policy and healthcare.",

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Boccia, S, Brand, A , Brand, H & Ricciardi, G 2009, 'The integration of genome-based information for common diseases into health policy and healthcare as a major challenge for Public Health Genomics: The example of the methylenetetrahydrofolate reductase gene in non-cancer diseases', Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, vol. 667, no. 1-2, pp. 27-34. https://doi.org/10.1016/j.mrfmmm.2008.10.003

The integration of genome-based information for common diseases into health policy and healthcare as a major challenge for Public Health Genomics: The example of the methylenetetrahydrofolate reductase gene in non-cancer diseases. / Boccia, Stefania; Brand, Angela ; Brand, Helmut et al.
In: Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, Vol. 667, No. 1-2, 10.07.2009, p. 27-34.

Research output: Contribution to journal › Article › peer-review

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Boccia S, Brand A , Brand H, Ricciardi G. The integration of genome-based information for common diseases into health policy and healthcare as a major challenge for Public Health Genomics: The example of the methylenetetrahydrofolate reductase gene in non-cancer diseases. Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 2009 Jul 10;667(1-2):27-34. doi: 10.1016/j.mrfmmm.2008.10.003

The integration of genome-based information for common diseases into health policy and healthcare as a major challenge for Public Health Genomics: The example of the methylenetetrahydrofolate reductase gene in non-cancer diseases

Abstract

All Science Journal Classification (ASJC) codes

UN SDGs

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