The: P -toluenesulfonic acid catalyzed single pot synthesis of tetracyclic 1,2-dihydroquinolines: A metal free approach

Anil K. Hajare; Arun R. Jagdale; G. Gautham Shenoy; Neelima Sinha

doi:10.1039/c6nj00928j

The: P -toluenesulfonic acid catalyzed single pot synthesis of tetracyclic 1,2-dihydroquinolines: A metal free approach

Anil K. Hajare
, Arun R. Jagdale
, G. Gautham Shenoy
, Neelima Sinha^*

^*Corresponding author for this work

Department of Pharmaceutical Chemistry, Manipal College of Pharmaceutical Sciences, Manipal

Research output: Contribution to journal › Article › peer-review

10 Citations (Scopus)

Abstract

A simple, convenient and efficient p-toluenesulfonic acid catalyzed tandem reaction of aliphatic ketones with substituted anilines towards the synthesis of polysubstituted 1,2-dihydroquinolines has been developed. The ready availability of the catalyst, operational simplicity, cost effectiveness of the process and excellent regioselectivity mark some of the highlights of this methodology.

Original language	English
Pages (from-to)	4888-4890
Number of pages	3
Journal	New Journal of Chemistry
Volume	40
Issue number	6
DOIs	https://doi.org/10.1039/c6nj00928j
Publication status	Published - 2016

All Science Journal Classification (ASJC) codes

Catalysis
General Chemistry
Materials Chemistry

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10.1039/c6nj00928j

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abstract = "A simple, convenient and efficient p-toluenesulfonic acid catalyzed tandem reaction of aliphatic ketones with substituted anilines towards the synthesis of polysubstituted 1,2-dihydroquinolines has been developed. The ready availability of the catalyst, operational simplicity, cost effectiveness of the process and excellent regioselectivity mark some of the highlights of this methodology.",

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AU - Shenoy, G. Gautham

AU - Sinha, Neelima

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AB - A simple, convenient and efficient p-toluenesulfonic acid catalyzed tandem reaction of aliphatic ketones with substituted anilines towards the synthesis of polysubstituted 1,2-dihydroquinolines has been developed. The ready availability of the catalyst, operational simplicity, cost effectiveness of the process and excellent regioselectivity mark some of the highlights of this methodology.

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The: P -toluenesulfonic acid catalyzed single pot synthesis of tetracyclic 1,2-dihydroquinolines: A metal free approach

Abstract

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